Evidence map›Paper›PMID 36971949›Full record

ArticlePhysical and engineering sciences in medicine2023

Intrafraction motion during CyberKnife® prostate SBRT: impact of imaging frequency and patient factors.

Clarecia Rose, Martin A Ebert, Godfrey Mukwada, Malgorzata Skorska, Suki Gill

Abstract read
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In one paragraph

Article in Physical and engineering sciences in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

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  4. Proof of concept of near real-time intra-fractional 3D monitoring of prostate position using a scheme based on the skeletonization of implanted marker images and recursive least squares approximation motion tracking.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clarecia RoseDepartment of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia. ClareciaRose@outlook.com.ORCID http://orcid.org/0000-0002-5967-6430
Martin A EbertDepartment of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
Godfrey MukwadaDepartment of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
Malgorzata SkorskaDepartment of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
Suki GillDepartment of Radiation Oncology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
The University of Western Australia · AUSir Charles Gairdner Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the relationship between imaging frequencies and prostate motion during CyberKnife stereotactic body radiotherapy (SBRT) for prostate cancer.

methodsIntrafraction displacement data for 331 patients who received treatment with CyberKnife for prostate cancer were retrospectively analysed. Prostate positions were tracked with a large variation in imaging frequencies. The percent of treatment time that patients remained inside various motion thresholds for both real and simulated imaging frequencies was calculated. Results: 84,920 image acquisitions over 1635 fractions were analysed. Fiducial distance travelled between consecutive images were less than 2, 3, 5, and 10 mm for 92.4%, 94.4%, 96.2%, and 97.7% of all consecutive imaging pairs respectively. The percent of treatment time that patients received adequate geometric coverage increased with more frequent imaging intervals. No significant correlations between age, weight, height, BMI, rectal, bladder or prostate volumes and intrafraction prostate motion were observed.

conclusionsThere are several combinations of imaging intervals and movement thresholds that may be suitable for consideration during treatment planning with respect to imaging and calculation of the margin between the clinical target volume and planning target volume (CTV-to-PTV), resulting in adequate geometric coverage for approximately 95% of treatment time. Rectal toxicities and treatment duration need to be considered when implementing combinations clinically.

Indexed as

Prostatic NeoplasmsRadiosurgeryHumansMaleProstateRadiotherapy Planning, Computer-AssistedRetrospective StudiesCyberKnifeImaging intervalsProstate motionStereotactic body radiotherapy

Identifiers

PMID36971949
OpenAlexW4361001352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.