Evidence map›Paper›PMID 36971906›Full record

ArticleIn vitro cellular & developmental biology. Animal2023

Immortalization of primary cells derived from the endangered Ryukyu long-furred rat.

Lanlan Bai, Noe Kikuchi, Takahiro Eitsuka, Himari Matsusaka, Kiyotaka Nakagawa, Masafumi Katayama, Keiko Ito, Miho Inoue-Murayama, Tohru Kiyono, Tomokazu Fukuda

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In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Lanlan BaiGraduate School of Science and Engineering, Iwate University, Morioka, Iwate, Japan. bailanlan2010@gmail.com.ORCID http://orcid.org/0000-0002-2414-3247
Noe KikuchiGraduate School of Science and Engineering, Iwate University, Morioka, Iwate, Japan.
Takahiro EitsukaGraduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan.
Himari MatsusakaGraduate School of Science and Engineering, Iwate University, Morioka, Iwate, Japan.
Kiyotaka NakagawaGraduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan.
Masafumi KatayamaEnvironmental Genomics Office, Biodiversity Division, National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan.
Keiko ItoAmami Dog and Cat Animal Hospital, Amami Island, Kagoshima, Japan.
Miho Inoue-MurayamaWildlife Research Center, Kyoto University, Kyoto, Japan.
Tohru KiyonoExploratory Oncology Research & Clinical Trial Center, National Cancer Center, Chiba, Japan. tkiyono@east.ncc.go.jp.
Tomokazu FukudaGraduate School of Science and Engineering, Iwate University, Morioka, Iwate, Japan. tomofukuda009@gmail.com.
Iwate University · JPTohoku University · JPChiba Cancer Center · JPKyoto University · JPNational Institute for Environmental Studies · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Ryukyu long-furred rat is an endangered species confined to the southernmost three small islands of Japan (Amami-Oshima, Tokunoshima, and Okinawa). Its population is rapidly decreasing because of roadkill, deforestation, and feral animals. To date, its genomic and biological information are poorly understood. In this study, we successfully immortalized Ryukyu long-furred rat cells by expressing a combination of cell cycle regulators, mutant cyclin-dependent kinase 4 (CDK4

Indexed as

TelomeraseAnimalsAntigens, Viral, TumorCell CycleCell DivisionCell LineRatsAntigens, Viral, TumorTelomeraseCellular regulatorsChromosomeImmortalizationRyukyu long-furred ratSV40 T antigen

Identifiers

PMID36971906
OpenAlexW4361000196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.