Evidence map›Paper›PMID 36971874›Full record

ReviewInternational urology and nephrology2023

A review on renal autologous cell transplantation: an investigational approach towards chronic kidney disease.

Sidar Copur, Furkan Yavuz, Adrian Covic, Mehmet Kanbay

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sidar CopurDepartment of Medicine, Koc University School of Medicine, 34010, Istanbul, Turkey.
Furkan YavuzDepartment of Medicine, Koc University School of Medicine, 34010, Istanbul, Turkey.
Adrian CovicDepartment of Nephrology, Grigore T. Popa University of Medicine, Iasi, Romania.
Mehmet KanbayDepartment of Medicine, Division of Nephrology, Koc University School of Medicine, Istanbul, Turkey. mkanbay@ku.edu.tr.ORCID http://orcid.org/0000-0002-1297-0675
Koç University · TRGrigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease is among the most common causes of mortality and morbidity in adult population with limited therapeutic approaches including various medications and kidney replacement therapies. Kidney transplantation is the gold standard therapeutic alternative for the management of chronic kidney disease; nonetheless, important drawbacks include the lack of adequate living or deceased donors, high rates of pre- and post-operative complications including surgical complications, infectious complications and medication-induced adverse effects. With the latest preclinical and in vitro studies demonstrating the potentiality of kidney cells obtained from diseased kidneys to convert into fully functional kidney cells lead to a novel therapeutic alternative referred as autologous selected renal cell transplantation. Even though the clinical studies investigating the efficiency and adverse effects of autologous selected renal cell transplantation are limited, it is no doubt promising. The need for future large-scale studies on chronic kidney disease patients from a diversity of etiologies is clear for the better establishment of the therapeutic potential of autologous selected renal cell transplantation. In this narrative review, our aim is to evaluate the role of renal autologous stem cell therapy in the management of chronic kidney disease.

Indexed as

Kidney TransplantationRenal Insufficiency, ChronicAdultCell TransplantationHumansKidneyTissue DonorsTransplantation, AutologousChronic renal insufficiencyKidney transplantationStem cellsTherapeutics

Identifiers

PMID36971874
OpenAlexW4361003406

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.