ArticleInternational urogynecology journal2023
A comparison of MRI-based pelvic floor support measures between young and old women with prolapse.
Article in International urogynecology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Perineal Membrane Structural Changes: An Unstudied Aspect of Prolapse.International urogynecology journal · 2026Article
- Comparative Analysis of Logistic Regression and Machine Learning Algorithms for Predicting De Novo Stress Urinary Incontinence or Symptomatic Worsening Following Pelvic Floor Reconstruction: A Multicenter Study.International journal of women's health · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
introduction and hypothesisWe sought to 1) test the hypothesis that young women (≤45 years) with pelvic organ prolapse have a higher prevalence of major levator ani muscle (LAM) defects than old women (≥70 years) with prolapse and 2) compare level II/III measurements between young and old women with prolapse and age-matched controls to evaluate age-related mechanistic differences in the disease process.
methodsA secondary analysis examined four groups of parous women: young prolapse (YPOP, n = 17); old prolapse (OPOP, n = 17); young controls (YC, n = 15); old controls, (OC, n = 13). Prolapse was defined as any compartment at or beyond the hymen with vaginal bulge symptoms. Genital hiatus (GH) was measured on clinical exam. Major LAM defects and level II/III measurements (UGH: urogenital hiatus, LA: levator area, and apex location) were assessed on MRI at rest and strain, and the difference (Δ) between measurements calculated. Principal component analysis was used to evaluate levator plate (LP) shape.
resultsMajor LAM defects occurred in 42% of YPOP and 47% of OPOP (p > .99). GH
conclusionsProlapse in young women cannot be solely explained by a higher LAM defect prevalence. GH size and other measures of level II/III pelvic support worsen with age regardless of prolapse status.
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