ArticleIrish journal of medical science2023
Adherence of patients with age-related macular degeneration to AREDS 2-recommended nutritional supplements.
Article in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Regular AREDS2 Supplement Use in Age-Related Macular Degeneration: Factors Associated with Supplementation, Medication Adherence, and Patient-Reported Barriers.Healthcare (Basel, Switzerland) · 2026Article
- Patient and Neighborhood Factors Influencing Glaucoma Medication Adherence.Journal of glaucoma · 2026Article
- A Sulfated Polysaccharide fromMarine drugs · 2025Article
- [Nutritional therapy in ophthalmology-patients' interest and motivation].Die Ophthalmologie · 2025Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Age-Related Eye Disease Study 2 (AREDS 2) proved the benefit of vitamin and mineral supplementation in preventing advanced age-related macular degeneration (AMD). AREDS 2 supplements are indicated for patients with either bilateral intermediate AMD (AREDS category 3) or unilateral neovascular AMD (AREDS category 4).
aimsThe aims of this telephone survey were to identify the rate of adherence of patients to AREDS 2 supplements and the factors associated with non-compliance in these patient groups.
methodsA patient telephone survey was conducted in an Irish tertiary care hospital. Patients were identified by chart review, and their AREDS categorization was reconfirmed. A telephone consultation was conducted with each patient to assess their compliance with the micronutrient supplements.
resultsWe identified 120 patients who met the AREDS criteria for supplementation. Of these, 103 patients were graded as category 4, and 17 patients were graded as category 3. Almost a fifth (18%) were current smokers. Under two-thirds (60%) of the patients were taking AREDS 2 supplements. Of the remainder, 83% of patients did not recall being advised of their benefit. The cost was cited by 10% of patients as a reason for non-compliance.
conclusionThe ophthalmologist not only has a duty of care to treat the neovascular complications of AMD, but they must also strive to improve patient compliance with AREDS supplements. The cessation of smoking needs to be actively promoted in order to stop preventable vision loss in patients with AMD.
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