Evidence map›Paper›PMID 36971764›Full record

ArticleJournal of studies on alcohol and drugs2023

Risk Factors for Binge Drinking in Young Adulthood: The Roles of Aggregate Genetic Liability and Impulsivity-Related Processes.

Séverine Lannoy, Jon Heron, Matthew Hickman, Alexis C Edwards

Open access · greenAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Séverine LannoyDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia.
Jon HeronPopulation Health Sciences, University of Bristol, Bristol, United Kingdom.
Matthew HickmanPopulation Health Sciences, University of Bristol, Bristol, United Kingdom.
Alexis C EdwardsDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, Virginia.
University of Bristol · GBVirginia Commonwealth University · US

Funding

The Etiology of Risk: Alcohol Use Disorder and Suicidal BehaviorR01AA027522 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Alexis C Edwards, Kristina Sundquist · 2019 to 2026
$3.5M
Pathways to Alcohol Use Disorders in ALSPAC: A Genetic-Developmental StudyR01AA018333 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M, KENDLER, KENNETH SEEDMAN · 2010 to 2014
$2.8M
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009NIAAA NIH HHS R01 AA018333NIAAA NIH HHS R01 AA027522Wellcome TrustWellcome Trust 217065/Z/19/Z
6 · The paper itself

Abstract

objectiveBinge drinking is characterized by excessive alcohol use and is widespread in youth. We explore the relationship between binge drinking's risk factors by considering (a) aggregate genetic liability (polygenic risk score [PGS]) for alcohol use and problems and (b) impulsivity-related processes. We examined whether the associations between PGS and binge drinking were mediated by impulsivity, with a possible shared genetic liability between alcohol phenotypes and impulsivity.

methodParticipants were from the Avon Longitudinal Study of Parents and Children (

resultsHigher binge drinking frequency was related to higher aggregate genetic liability for alcohol use and problems in both models (standardized betas = .055-.064, all

conclusionsTargeting sensation seeking at the end of adolescence may be means to prevent binge drinking in adulthood, whereas considering the role of genetic factors may improve our understanding of at-risk youth.

Indexed as

Binge DrinkingAlcohol DrinkingEthanolHumansImpulsive BehaviorLongitudinal StudiesRisk FactorsEthanol

Identifiers

PMID36971764
PMCPMC10488311
OpenAlexW4322625854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.