Evidence map›Paper›PMID 36971264›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes.

Hasan Yakan, Gürkan Bilir, Şükriye Çakmak, Ömer Taş, Nalan Türköz Karakullukçu, Ercan Soydan, Halil Kütük, Coşkun Güçlü, Murat Şentürk, Tayfun Arslan and 3 more

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In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hasan YakanFaculty of Education, Department of Science and Mathematics Education, Ondokuz Mayis University, Samsun, Türkiye.ORCID 0000-0002-4428-4696
Gürkan BilirFaculty of Agriculture, Department of Agricultural Biotechnology, Ondokuz Mayıs University, Samsun, Türkiye.ORCID 0000-0003-3526-6610
Şükriye ÇakmakVocational School, Environmental Health Programme, Sinop University, Sinop, Türkiye.ORCID 0000-0002-2221-0098
Ömer TaşFaculty of Agriculture, Department of Agricultural Biotechnology, Ondokuz Mayıs University, Samsun, Türkiye.ORCID 0000-0003-1782-8210
Nalan Türköz KarakullukçuKaradeniz Advanced Technology Research and Application Centre, Ondokuz Mayis University, Samsun, Türkiye.
Ercan SoydanFaculty of Agriculture, Department of Agricultural Biotechnology, Ondokuz Mayıs University, Samsun, Türkiye.ORCID 0000-0002-9691-4434
Halil KütükFaculty of Arts and Sciences, Department of Chemistry, Ondokuz Mayis University, Samsun, Türkiye.ORCID 0000-0002-8135-7874
Coşkun GüçlüFaculty of Agriculture, Department of Agricultural Biotechnology, Eskisehir Osmangazi University, Eskisehir, Türkiye.ORCID 0000-0002-0248-0592
Murat ŞentürkDepartment of Biochemistry, Faculty of Paharnacy, Agri Ibrahim Cecen University, Agri, Türkiye.ORCID 0000-0002-9638-2896
Tayfun ArslanDepartment of Chemistry, Faculty of Arts and Sciences, Giresun University, Giresun, Türkiye.ORCID 0000-0002-1426-5857
Seyhan ÖztürkFaculty of Arts and Sciences, Department of Chemistry, Ondokuz Mayis University, Samsun, Türkiye.ORCID 0000-0003-4638-5578
Ercüment AksakalDepartment of Agricultural Biotechnology, Division of Animal Biotechnology, Agriculture Faculty, Akdeniz University, Antalya, Türkiye.ORCID 0000-0002-6871-8698
Deniz EkinciFaculty of Agriculture, Department of Agricultural Biotechnology, Ondokuz Mayıs University, Samsun, Türkiye.ORCID 0000-0001-7849-4117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of sulfenimide derivatives (1a-i) were investigated as inhibitors of human (hCA-I, hCA-II) and bovine (bCA) carbonic anhydrase enzymes. The compounds were synthesised by the reaction of substituted thiophenols with phthalimide by means of an effective, simple and eco-friendly method and the structures were confirmed by IR,

Indexed as

Carbonic AnhydrasesAnimalsCarbonic Anhydrase ICarbonic Anhydrase IICarbonic Anhydrase InhibitorsCattleHumansMolecular StructureStructure-Activity RelationshipCarbonic Anhydrase ICarbonic Anhydrase IICarbonic Anhydrase InhibitorsCarbonic AnhydrasesCarbonic anhydraseinhibitorphthalimidesulfenimidethiophenol

Identifiers

PMID36971264
PMCPMC10044159

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read13
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.