ArticleTurk psikiyatri dergisi = Turkish journal of psychiatry2023
Evaluation of Simple Markers of Inflammation and Systemic Immune Inflammation Index in Schizophrenia, Bipolar Disorder Patients and Healthy Controls.
Article in Turk psikiyatri dergisi = Turkish journal of psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Complete blood count-based inflammatory ratios in people with bipolar disorder: a systematic review and meta-analysis of neutrophil-to-lymphocyte, monocyte-to-lymphocyte, and platelet-to-lymphocyte ratios.European psychiatry : the journal of the Association of European Psychiatrists · 2026Pooled it
- Distributional Characterization of CBC-Derived Inflammatory Indices in Hospitalized Patients with Schizophrenia.Diagnostics (Basel, Switzerland) · 2026Article
- Complete Blood-Count-Derived Inflammatory Markers Across Acute Mood Episodes.Alpha psychiatry · 2026Article
- Inflammatory and Metabolic Blood Parameters Associated with Aggression, Impulsivity, and Suicide Risk Among Male Patients with Antisocial Personality Disorder in a Forensic Psychiatry Unit in Turkey: A Cross-Sectional Comparative Study.Diagnostics (Basel, Switzerland) · 2026Article
- Investigation of Peripheral Inflammatory Biomarkers in Trichotillomania.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2026Article
- Evaluation of Inflammatory Markers in Perception Disorders in Major Psychiatric Pathology.International journal of molecular sciences · 2025Article
- Evaluation of Pan-immune Inflammation Value and Systemic Immune Inflammation Index in Different Mood Episodes of Bipolar Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- The Correlation of Blood Immune Cells with the Pathogenesis of Schizophrenia: A Meta-Analysis.Iranian journal of public health · 2025Review
- Article
- Hematological and biochemical markers and cytokine levels in hospitalized psychiatric patients with COVID-19.Frontiers in immunology · 2025Article
- An Exploratory Study of Inflammatory Biomarkers and Extrapyramidal Side Effects in Patients with Schizophrenia.Schizophrenia bulletin open · 2025Article
- Neutrophil-to-lymphocyte, platelet-to-lymphocyte ratios and systemic immune-inflammation index in patients with post-traumatic stress disorder.BMC psychiatry · 2024Article
- Evaluation of Complete Blood Cell Count Parameters and Their Role in Inflammation in Patients with Methamphetamine and Synthetic Cannabis Use Disorder.Psychiatry and clinical psychopharmacology · 2024Article
- Evaluation of primary markers of inflammation and the systemic inflammation index in specific learning disabilities.Biomarkers in medicine · 2024Article
- Inflammation Markers in Patients with Bipolar Disorder Who Have Committed Offenses and Their Relationship with Criminal Behavior.Medicina (Kaunas, Lithuania) · 2023Article
- The Relationship of Cognitive Dysfunction with Inflammatory Markers and Carotid Intima Media Thickness in Schizophrenia.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveNeutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), mean platelet volume (MPV), and systemic immune inflammation index (SII) are recently used as indicators of inflammation. NLR, PLR, MLR, and MPV have been evaluated in many studies in patients with schizophrenia and bipolar disorder. However, there are no studies investigating SII. This study aims to evaluate NLR, PLR, MLR, MPV and SII values and complete blood count elements in patients hospitalized with diagnoses of the schizophrenia with psychotic episode and bipolar disorder with manic episode by comparing them with the control group.
methodA total of 149 patients who were hospitalized with the diagnoses of the schizophrenia with psychotic episode and bipolar disorder with manic episode and who met the inclusion criteria were included in our study where the control group was composed of 66 healthy individuals. White blood cell (WBC), neutrophil, lymphocyte, platelet, and monocyte counts were obtained retrospectively from complete blood counts at the time of admission, based on which NLR, PLR, MLR, and SII were calculated.
resultsIn this study, higher NLR, PLR, and SII values and lower MPV and lymphocyte counts were observed in schizophrenia patients compared to the control group. NLR, PLR, and SII values and neutrophil counts were higher in patients with bipolar disorder compared to the control group. Lower MPV values were found in patients with schizophrenia compared to patients with bipolar disorder.
conclusionSimple inflammatory and SII values in our study indicate the presence of low-grade systemic inflammation in schizophrenia and bipolar disorder.
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