Evidence map›Paper›PMID 36970749›Full record

ArticleDalton transactions (Cambridge, England : 2003)2023

New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders.

Florêncio Sousa Gouveia Júnior, João Alison de Moraes Silveira, Thais Muratori Holanda, Aline Diogo Marinho, Lisa A Ridnour, David A Wink, Rodrigo José Bezerra de Siqueira, Helena Serra Azul Monteiro, Eduardo Henrique Silva de Sousa, Luiz Gonzaga de França Lopes

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dalton transactions (Cambridge, England : 2003), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 13 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Florêncio Sousa Gouveia JúniorLaboratory of Bioinorganic Chemistry, Department of Organic and Inorganic Chemistry, Federal University of Ceara, 60455-760, Fortaleza-CE, Brazil. eduardohss@dqoi.ufc.br.ORCID http://orcid.org/0000-0003-1624-8740
João Alison de Moraes SilveiraDepartment of Physiology and Pharmacology, School of Medicine, Federal University of Ceara, Coronel Nunes de Melo St., 1127, 60.430-275, Fortaleza-CE, Brazil.
Thais Muratori HolandaDepartment of Physiology and Pharmacology, School of Medicine, Federal University of Ceara, Coronel Nunes de Melo St., 1127, 60.430-275, Fortaleza-CE, Brazil.
Aline Diogo MarinhoDrug Research and Development Center (NPDM), Federal University of Ceara, Coronel Nunes de Melo St., 1000, 60.430-275, Fortaleza-CE, Brazil.
Lisa A RidnourNational Cancer Institute, Cancer and Inflammation Program, Frederick, Maryland 21702, USA.
David A WinkNational Cancer Institute, Cancer and Inflammation Program, Frederick, Maryland 21702, USA.
Rodrigo José Bezerra de SiqueiraDepartment of Physiology and Pharmacology, School of Medicine, Federal University of Ceara, Coronel Nunes de Melo St., 1127, 60.430-275, Fortaleza-CE, Brazil.
Helena Serra Azul MonteiroDepartment of Physiology and Pharmacology, School of Medicine, Federal University of Ceara, Coronel Nunes de Melo St., 1127, 60.430-275, Fortaleza-CE, Brazil.
Eduardo Henrique Silva de SousaLaboratory of Bioinorganic Chemistry, Department of Organic and Inorganic Chemistry, Federal University of Ceara, 60455-760, Fortaleza-CE, Brazil. eduardohss@dqoi.ufc.br.ORCID http://orcid.org/0000-0002-0007-8452
Luiz Gonzaga de França LopesLaboratory of Bioinorganic Chemistry, Department of Organic and Inorganic Chemistry, Federal University of Ceara, 60455-760, Fortaleza-CE, Brazil. eduardohss@dqoi.ufc.br.ORCID http://orcid.org/0000-0002-3641-1835
Universidade Federal do Ceará · BRNational Cancer Institute · US

Funding

Redox Mechanism Process of Nos2 and COX2 in Stroma tumor interactionZIABC010898 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WINK, DAVID · 2009 to 2025
$8.6M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Nitrosyl ruthenium complexes are promising platforms for nitric oxide (NO) and nitroxyl (HNO) release, which exert their therapeutic application. In this context, we developed two polypyridinic compounds with the general formula

Indexed as

Coordination ComplexesRutheniumAnimalsCardiovascular DiseasesNitric OxideNitrogen OxidesRatsSulfhydryl CompoundsCoordination ComplexesNitric OxideNitrogen OxidesnitroxylRutheniumSulfhydryl Compounds

Identifiers

PMID36970749
PMCPMC10168103
OpenAlexW4323777704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.