Evidence map›Paper›PMID 36970720›Full record

Observational studyCancer research communications2022

Identifying Good Candidates for Active Surveillance of Ductal Carcinoma

Alexa C Glencer, Phoebe N Miller, Heather Greenwood, Cristian K Maldonado Rodas, Rita Freimanis, Amrita Basu, Rita A Mukhtar, Case Brabham, Paul Kim, E Shelley Hwang and 5 more

Open access · goldFull text readObservational Study
In one paragraph

Observational study in Cancer research communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Alexa C Glencer *Department of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0002-3183-1056
Phoebe N Miller *University of California San Francisco School of Medicine, San Francisco, California.ORCID 0000-0002-3938-3606
Heather GreenwoodDepartment of Radiology, University of California San Francisco, San Francisco, California.ORCID 0000-0001-7664-3852
Cristian K Maldonado RodasDepartment of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0003-0096-9316
Rita FreimanisDepartment of Radiology, University of California San Francisco, San Francisco, California.ORCID 0000-0001-5229-8687
Amrita BasuDepartment of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0001-5005-3803
Rita A MukhtarDepartment of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0001-8079-7846
Case BrabhamHarvard Medical School, Boston, Massachusetts.ORCID 0000-0003-3393-4857
Paul KimQuinnipiac University School of Medicine, North Haven, Connecticut.ORCID 0000-0001-9271-9431
E Shelley HwangDepartment of Surgery, Duke University, Durham, North Carolina.ORCID 0000-0002-8571-1148
Jennifer M RosenbluthDepartment of Medicine, University of California San Francisco, San Francisco, California.ORCID 0000-0003-1314-6976
Gillian L HirstDepartment of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0002-4502-0035
Michael J CampbellDepartment of Surgery, University of California San Francisco, San Francisco, California.
Alexander D BorowskyDepartment of Pathology, University of California Davis, Sacramento, California.ORCID 0000-0003-3117-9202
Laura J EssermanDepartment of Surgery, University of California San Francisco, San Francisco, California.ORCID 0000-0001-9202-4568
University of California, San Francisco · USDuke University · USHarvard University · USQuinnipiac University · USUniversity of California, Davis · US

Funding

Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancersU01CA196406 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BOROWSKY, ALEXANDER D, ESSERMAN, LAURA J · 2015 to 2020
$5.8M
Integrated Biomarkers to Characterize Breast Cancer RiskU01CA111234 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ESSERMAN, LAURA J · 2004 to 2009
$4.4M
Surgical Oncology Training GrantT32CA251070 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ESSERMAN, LAURA J · 2020 to 2024
$1.5M
NCI NIH HHS T32 CA251070NCI NIH HHS U01 CA111234NCI NIH HHS U01 CA196406
6 · The paper itself

Abstract

Ductal carcinoma Significance: A retrospective analysis of 71 patients with DCIS who did not undergo upfront surgery demonstrated that breast MRI features after short-term exposure to endocrine therapy identify those at high (68.2%), intermediate (20.0%), and low risk (8.7%) of IDC. With 7.4 years mean follow-up, 52.1% of patients remain on active surveillance. A period of active surveillance offers the opportunity to risk-stratify DCIS lesions and guide decisions for operative management.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingFemaleHumansNeoadjuvant TherapyRetrospective StudiesWatchful Waiting

Identifiers

PMID36970720
PMCPMC10035518
OpenAlexW4309758026

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read89
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.