Evidence map›Paper›PMID 36970713›Full record

ArticleInternational journal of pharmaceutics: X2023

PK-PD Evaluation of Inhaled Microparticles loaded with Ciprofloxacin-Copper complex in a Rat Model of Chronic

Frederic Tewes, Barbara Lamy, Julian Laroche, Isabelle Lamarche, Sandrine Marchand

Open access · goldAbstract read
In one paragraph

Article in International journal of pharmaceutics: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Lung microdialysis andFrontiers in veterinary science · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Frederic TewesUniversité de Poitiers, INSERM U1070, Poitiers, France.
Barbara LamyUniversité de Poitiers, INSERM U1070, Poitiers, France.
Julian LarocheCHU de Poitiers, laboratoire de Toxicologie et de Pharmacocinetique, Poitiers, France.
Isabelle LamarcheUniversité de Poitiers, INSERM U1070, Poitiers, France.
Sandrine MarchandUniversité de Poitiers, INSERM U1070, Poitiers, France.
Centre Hospitalier Universitaire de Poitiers · FRInserm · FRPharmacologie des anti-infectieux et antibiorésistance

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential gain in efficacy of pulmonary administration over IV administration of some antibiotics such as ciprofloxacin (CIP) may be limited by the short residence time of the drug at the site of infection after nebulization. Complexation of CIP with copper reduced its apparent permeability

Indexed as

Inhaled antibioticsLung infectionsPharmacodynamicsPharmacokineticsPseudomonas aeruginosaPulmonary administration

Identifiers

PMID36970713
PMCPMC10033950
OpenAlexW4323922502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.