Evidence map›Paper›PMID 36970660›Full record

ArticleFrontiers in microbiology2023

Optimization of the growth conditions through response surface methodology and metabolomics for maximizing the auxin production by

Francesca Melini, Francesca Luziatelli, Paolo Bonini, Anna Grazia Ficca, Valentina Melini, Maurizio Ruzzi

Open access · goldFull text read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Optimization of auxin production by Streptomyces californicus CLV91 for plant growth promotion.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Francesca MeliniDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, Viterbo, Italy.
Francesca LuziatelliDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, Viterbo, Italy.
Paolo BoniniOloBion-OMICS LIFE LAB, Barcelona, Spain.
Anna Grazia FiccaDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, Viterbo, Italy.
Valentina MeliniCREA Research Centre for Food and Nutrition, Rome, Italy.
Maurizio RuzziDepartment for Innovation in Biological, Agrofood and Forest Systems, University of Tuscia, Viterbo, Italy.
Università degli Studi della Tuscia · ITCereal Research Centre · ITNanobionics (Brazil) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The fermentative production of auxin/indole 3-acetate (IAA) using selected Methods: By integrating metabolomics and fermentation technologies, this study aimed to define the optimal culture conditions to obtain auxin/IAA-enriched plant postbiotics using Results and discussion: Array of compounds with plant growth-promoting- (IAA and hypoxanthine) and biocontrol activity (NS-5, cyclohexanone, homo-L-arginine, methyl hexadecenoic acid, and indole-3-carbinol) can be stimulated by cultivating this strain on minimal saline medium amended with sucrose as a carbon source. We applied a three-level-two-factor central composite design (CCD) based response surface methodology (RSM) to explore the impact of the independent variables (rotation speed and medium liquid-to-flask volume ratio) on the production of IAA and IAA precursors. The ANOVA component of the CCD indicated that all the process-independent variables investigated significantly impacted the auxin/IAA production by

Indexed as

auxinmetabolomicsPantoea agglomeransplant growth-promoting rhizobacteriapostbioticsresponse surface methodology

Identifiers

PMID36970660
PMCPMC10030972
OpenAlexW4323567735

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read6
measurements read57
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.