ArticleWorld journal of gastroenterology2023
Quantitative parameters in novel spectral computed tomography: Assessment of Ki-67 expression in patients with gastric adenocarcinoma.
Article in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 25 citations in OpenAlex.
- Whole-volume histogram analysis of spectral-computed tomography iodine maps characterizes HER2 expression in gastric cancer.World journal of gastroenterology · 2024Trial
- Spectral CT-based Nomogram for Noninvasive Assessment and Prognostic Prediction of MSI/dMMR in Esophagogastric Junction Adenocarcinoma.Radiology. Imaging cancer · 2026Article
- Predictive imaging in abdominal oncology: current trends and future directions.Japanese journal of radiology · 2026Review
- Research progress of the clinical application of dual-layer spectral computed tomography in gastrointestinal malignancies.World journal of radiology · 2026Review
- Dual-layer spectral detector CT: a non-invasive tool for simultaneously predicting Ki-67 proliferation status and p53 mutations in pancreatic ductal adenocarcinoma.Abdominal radiology (New York) · 2026Article
- Noninvasive evaluation of treatment-related protein expression status in advanced gastric cancer using dynamic nomograms with dual-energy CT: a multicenter study.European radiology · 2026Article
- Precision imaging biomarkers for gout: artifact-specific spectral CT parameters for personalized differentiation of tophi in a prospective study.Therapeutic advances in musculoskeletal disease · 2026Article
- Comparison of 2D and 3D measured iodine concentration of gastric adenocarcinoma on spectral-CT and their relationship with perineural invasion.BMC medical imaging · 2025Article
- Development and validation of a fusion model based on multi-phase contrast CT radiomics combined with clinical features for predicting Ki-67 expression in gastric cancer.Biomedical reports · 2025Article
- The clinical applications of dual-layer spectral detector CT in digestive system diseases.European radiology · 2025Review
- Spectral CT-based nomogram for preoperative prediction of Lauren classification in locally advanced gastric cancer: a prospective study.European radiology · 2025Article
- Performance of novel multiparametric second-generation dual-layer spectral detector CT in gouty arthritis.European radiology · 2025Article
- Spectral computed tomography parameters for predicting vessels encapsulating tumor clusters (VETC) pattern in hepatocellular carcinoma: a pilot study.Quantitative imaging in medicine and surgery · 2025Article
- Evaluation of Ki-67 expression levels in esophageal squamous cell carcinoma using dual-energy CT quantitative parameters.Frontiers in oncology · 2025Article
- ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation.Frontiers in oncology · 2025Article
- Radiomics model based on dual-energy CT venous phase parameters to predict Ki-67 levels in gastrointestinal stromal tumors.Frontiers in oncology · 2025Article
- Preoperative prediction of Ki-67 expression in hepatocellular carcinoma by spectral imaging on dual-energy computed tomography (DECT).Quantitative imaging in medicine and surgery · 2024Article
- Development and validation of a model based on preoperative dual-layer detector spectral computed tomography 3D VOI-based quantitative parameters to predict high Ki-67 proliferation index in pancreatic ductal adenocarcinoma.Insights into imaging · 2024Article
- Differentiation of pathological subtypes and Ki-67 and TTF-1 expression by dual-energy CT (DECT) volumetric quantitative analysis in non-small cell lung cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundThe level of Ki-67 expression has served as a prognostic factor in gastric cancer. The quantitative parameters based on the novel dual-layer spectral detector computed tomography (DLSDCT) in discriminating the Ki-67 expression status are unclear.
aimTo investigate the diagnostic ability of DLSDCT-derived parameters for Ki-67 expression status in gastric carcinoma (GC).
methodsDual-phase enhanced abdominal DLSDCT was performed preoperatively in 108 patients with gastric adenocarcinoma. Primary tumor monoenergetic CT attenuation value at 40-100 kilo electron volt (kev), the slope of the spectral curve (λ
resultsThirty-seven and 71 patients were classified as having low and high Ki-67 expression, respectively. CT
conclusionQuantitative spectral parameters are feasible to distinguish low and high Ki-67 expression in gastric adenocarcinoma. Z
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