Evidence map›Paper›PMID 36970526›Full record

ArticleFrontiers in neurology2023

Tracking auditory mismatch negativity responses during full conscious state and coma.

Adianes Herrera-Diaz, Rober Boshra, Paniz Tavakoli, Chia-Yu A Lin, Netri Pajankar, Elham Bagheri, Richard Kolesar, Alison Fox-Robichaud, Cindy Hamielec, James P Reilly and 1 more

Open access · goldFull text read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Adianes Herrera-DiazCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
Rober BoshraPrincenton Neuroscience Institute, Princeton University, Princeton, NJ, United States.
Paniz TavakoliCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
Chia-Yu A LinCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
Netri PajankarCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
Elham BagheriCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
Richard KolesarDepartment of Anesthesia, McMaster University, Hamilton, ON, Canada.
Alison Fox-RobichaudDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Cindy HamielecDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
James P ReillyCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
John F ConnollyCentre for Advanced Research in Experimental and Applied Linguistics (ARiEAL), McMaster University, Hamilton, ON, Canada.
McMaster University · CAHamilton Health Sciences · CAOntario Neurotrauma Foundation · CAPrinceton University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mismatch negativity (MMN) is considered the electrophysiological change-detection response of the brain, and therefore a valuable clinical tool for monitoring functional changes associated with return to consciousness after severe brain injury. Using an auditory multi-deviant oddball paradigm, we tracked auditory MMN responses in seventeen healthy controls over a 12-h period, and in three comatose patients assessed over 24 h at two time points. We investigated whether the MMN responses show fluctuations in detectability over time in full conscious awareness, or whether such fluctuations are rather a feature of coma. Three methods of analysis were utilized to determine whether the MMN and subsequent event-related potential (ERP) components could be identified: traditional visual analysis, permutation

Indexed as

brain injurycomadisorder of consciousnessevent-related potentials (ERP)mismatch negativity

Identifiers

PMID36970526
PMCPMC10036371
OpenAlexW4323862666

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.