Evidence map›Paper›PMID 36970494›Full record

ArticleLancet regional health. Americas2023

The impact of sustained malaria control in the Loreto region of Peru: a retrospective, observational, spatially-varying interrupted time series analysis of the PAMAFRO program.

Mark M Janko, G Cristina Recalde-Coronel, Camila P Damasceno, Gabriela Salmón-Mulanovich, Alisson F Barbieri, Andrés G Lescano, Benjamin F Zaitchik, William K Pan

Open access · goldFull text read
In one paragraph

Article in Lancet regional health. Americas, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Malaria control and the unexpected spread of diagnostic-resistantbioRxiv : the preprint server for biology · 2026
    Article
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  8. Between their own and the western: the experience of Emberá communities in Chocó with Malaria.Revista peruana de medicina experimental y salud publica · 2025
    Article
  9. Article
  10. Molecular Screening ofAnimals : an open access journal from MDPI · 2025
    Article
  11. Article
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  14. Associations between weather andmedRxiv : the preprint server for health sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Mark M JankoDuke Global Health Institute, Duke University, Durham, NC, USA.
G Cristina Recalde-CoronelDepartment of Earth and Planetary Sciences, Johns Hopkins University, Baltimore, MD, USA.
Camila P DamascenoUniversidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Gabriela Salmón-MulanovichPontifica Universidad Catolica del Peru, Lima, Peru.
Alisson F BarbieriUniversidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Andrés G LescanoClima, Latin American Center of Excellence for Climate Change and Health, and Emerge, Emerging Diseases and Climate Change Research Unit, Universidad Peruana Cayetano Heredia, Lima, Peru.
Benjamin F ZaitchikDepartment of Earth and Planetary Sciences, Johns Hopkins University, Baltimore, MD, USA.
William K PanDuke Global Health Institute, Duke University, Durham, NC, USA.
Duke University · USJohns Hopkins University · USUniversidade Federal de Minas Gerais · BRPontificia Universidad Católica del Perú · PEUniversidad Peruana Cayetano Heredia · PE

Funding

SARS-CoV-2 genomic variant surveillance in human and non-human primate populations in PeruU01AI151814 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BARKER, CHRISTOPHER M, COFFEY, LARK L · 2020 to 2024
$8.9M
Peru Infectious Diseases Epidemiology Research Training ConsortiumD43TW007393 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Andres G Lescano · 2005 to 2026
$5.9M
Improving Response to Malaria Outbreaks in Amazon-Basin CountriesR01AI151056 · NIAID · DUKE UNIVERSITY · PI PAN, WILLIAM KUANG-YAO · 2021 to 2025
$3.4M
FIC NIH HHS D43 TW007393NIAID NIH HHS R01 AI151056NIAID NIH HHS U01 AI151814
6 · The paper itself

Abstract

Background: Although malaria control investments worldwide have resulted in dramatic declines in transmission since 2000, progress has stalled. In the Amazon, malaria resurgence has followed withdrawal of Global Fund support of the Project for Malaria Control in Andean Border Areas (PAMAFRO). We estimate intervention-specific and spatially-explicit effects of the PAMAFRO program on malaria incidence across the Loreto region of Peru, and consider the influence of the environmental risk factors in the presence of interventions. Methods: We conducted a retrospective, observational, spatial interrupted time series analysis of malaria incidence rates among people reporting to health posts across Loreto, Peru between the first epidemiological week of January 2001 and the last epidemiological week of December 2016. Model inference is at the smallest administrative unit (district), where the weekly number of diagnosed cases of Findings: During the PAMAFRO program, incidence of Interpretation: Malaria control programs must consider the climate and environmental scope of interventions to maximize effectiveness. They must also ensure financial sustainability to maintain local progress and commitment to malaria prevention and elimination efforts, as well as to offset the effects of environmental change that increase transmission risk. Funding: National Aeronautics and Space Administration, National Institutes of Health, Bill and Melinda Gates Foundation.

Indexed as

ClimateInterrupted time seriesLoretoMalariaPAMAFROSpatially-varying coefficients

Identifiers

PMID36970494
PMCPMC10036736
OpenAlexW4327596352

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read78
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.