Evidence map›Paper›PMID 36970462›Full record

ArticleJournal of traditional and complementary medicine2023

Cell-free

Letizia Vallino, Beatrice Garavaglia, Annalisa Visciglia, Angela Amoruso, Marco Pane, Alessandra Ferraresi, Ciro Isidoro

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

  1. Food science & nutrition · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. BioImpacts : BI · 2025
    Article
  10. Review
  11. Appraisal of postbiotics in cancer therapy.Frontiers in pharmacology · 2024
    Review
  12. Three-DimensionalInternational journal of biological sciences · 2024
    Review
  13. Review
  14. Editorial note: Gut microbiota and health.Journal of traditional and complementary medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Letizia VallinoLaboratory of Molecular Pathology, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Via P. Solaroli 17, 28100, Novara, Italy.
Beatrice GaravagliaLaboratory of Molecular Pathology, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Via P. Solaroli 17, 28100, Novara, Italy.
Annalisa ViscigliaProbiotical Research Srl, via E. Mattei, 3, 28100, Novara, Italy.
Angela AmorusoProbiotical Research Srl, via E. Mattei, 3, 28100, Novara, Italy.
Marco PaneProbiotical Research Srl, via E. Mattei, 3, 28100, Novara, Italy.
Alessandra FerraresiLaboratory of Molecular Pathology, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Via P. Solaroli 17, 28100, Novara, Italy.
Ciro IsidoroLaboratory of Molecular Pathology, Department of Health Sciences, Università del Piemonte Orientale "A. Avogadro", Via P. Solaroli 17, 28100, Novara, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITProbiotical (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: Gut microbiota is considered as a complex organ of human body. The interaction between the host and microbiota is dynamic and controlled by a huge number of factors, such as lifestyle, geography, pharmaceuticals, diet, and stress. The breakdown of this relationship could change microbiota composition favoring the onset of several diseases, including cancer. Metabolites released by microbiota bacterial strains have been reported to elicit protective effects on the mucosa that could contrast cancer development and progression. Here, we tested the ability of specific probiotic strain Experimental procedure: The study was performed on two cell lines, HCT116 and HT29, cultured in 2D and 3D, and focused on the hallmarks of cell proliferation and migration. Results and conclusion: Probiotic metabolites reduced cell proliferation both in 2D and 3D-spheroid cultures, the latter model mimicking the growth

Indexed as

AutophagyButyrateCell migrationCell proliferationColorectal cancerInflammationMicrobiotaProbioticsβ-Catenin

Identifiers

PMID36970462
PMCPMC10037073
OpenAlexW4321502924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.