ReviewFrontiers in cardiovascular medicine2023
Polymeric prosthetic heart valves: A review of current technologies and future directions.
Review in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Hematologic complications and design challenges in cardiovascular devices.Communications engineering · 2026Review
- Innovation and Challenges in Materials for Transcatheter Aortic Valves.Journal of cardiovascular translational research · 2026Review
- Identification of Autologous Tissue Sources and Optimization of a Treatment Method for Intraoperative Manufacturing of Heart Valve Constructs.Artificial organs · 2026Article
- From Polymer Structure to Valve Function: A Multiscale Evaluation of Polycarbonate Polyurethanes for Polymeric Mitral Valves.Annals of biomedical engineering · 2026Article
- Pyriphenone modification of glutaraldehyde pretreated bovine pericardium mitigates advanced glycation end products, calcification, and platelet adhesion.Acta biomaterialia · 2026Article
- Current Trends and Future Challenges in Transcatheter Aortic Valve Implantation (TAVI): A Narrative Review.Journal of clinical medicine · 2026Review
- Material-Driven Clinical Complications in Mechanical Circulatory Support: From Blood-Material Interactions to Device-Related Adverse Events.Materials (Basel, Switzerland) · 2026Review
- Alpha-gal xenoantigens in bioprosthetic valve recipients: clinical implications for bioprosthesis longevity.Journal of cardiothoracic surgery · 2026Review
- Current trends, applications, and challenges in three-dimensional bioprinting for cardiovascular disease models and therapies.iScience · 2026Review
- [Numerical simulation study on the influence of free edge configuration on the performance of polymeric heart valves].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Article
- Design and preclinical feasibility of a pediatric heart valve stent that spontaneously adapts to growth via a spring mechanism.Science advances · 2026Article
- Development of a Polymeric TAVR Device Tailored to Bicuspid Aortic Valve Patients Using In Silico Design Optimization and Evaluation.Annals of biomedical engineering · 2026Article
- The "Cairo Accord"- towards the eradication of RHD: revisited (2026).Frontiers in cardiovascular medicine · 2026Review
- From Last Resort to Standard of Care: The Evolution and Future of Transcatheter Aortic Valve Implantation.Reviews in cardiovascular medicine · 2026Review
- Woven solutions for tissue engineering: Next-generation heart valves from fiber to function.American heart journal plus : cardiology research and practice · 2025Article
- Advancements and Perspectives in the Bioprosthetic Heart Valve: A Comprehensive Review on Biomaterial Processing and Emerging Polymeric Materials.Journal of the American Heart Association · 2025Review
- The Next Chapter in TAVR: Innovations and the Road Ahead.Journal of clinical medicine · 2025Review
- Replacement as an aging intervention.Nature aging · 2025Review
- Biomimetic Polyurethanes in Tissue Engineering.Biomimetics (Basel, Switzerland) · 2025Review
- Transcatheter Aortic Valve Implantation and Replacement: The Latest Advances and Prospects.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Valvular heart disease is an important source of cardiovascular morbidity and mortality. Current prosthetic valve replacement options, such as bioprosthetic and mechanical heart valves are limited by structural valve degeneration requiring reoperation or the need for lifelong anticoagulation. Several new polymer technologies have been developed in recent years in the hope of creating an ideal polymeric heart valve substitute that overcomes these limitations. These compounds and valve devices are in various stages of research and development and have unique strengths and limitations inherent to their properties. This review summarizes the current literature available for the latest polymer heart valve technologies and compares important characteristics necessary for a successful valve replacement therapy, including hydrodynamic performance, thrombogenicity, hemocompatibility, long-term durability, calcification, and transcatheter application. The latter portion of this review summarizes the currently available clinical outcomes data regarding polymeric heart valves and discusses future directions of research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.