Evidence map›Paper›PMID 36970169›Full record

ArticleNeuro-oncology practice2023

Neurocognitive function and health-related quality of life in a nationwide cohort of long-term childhood brain tumor survivors.

Anne Sophie L Helligsoe, Louise T Henriksen, Line Kenborg, Yasmin Lassen-Ramshad, Lisa M Wu, Jeanette F Winther, Henrik Hasle, Ali Amidi

Open access · bronzeAbstract read
In one paragraph

Article in Neuro-oncology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anne Sophie L HelligsoeDepartment of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.ORCID https://orcid.org/0000-0003-4956-4897
Louise T HenriksenDepartment of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.ORCID https://orcid.org/0000-0002-9350-1538
Line KenborgChildhood Cancer Research Group, Danish Cancer Society Research Center, Denmark.ORCID https://orcid.org/0000-0002-3584-6570
Yasmin Lassen-RamshadDanish Centre for Particle Therapy, Aarhus University Hospital, Denmark.ORCID https://orcid.org/0000-0002-4992-3231
Lisa M WuUnit for Psychooncology & Health Psychology, Department of Psychology and Behavioural Sciences, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0003-2241-9905
Jeanette F WintherDepartment of Clinical Medicine, Faculty of Health, Aarhus University, Denmark.ORCID https://orcid.org/0000-0002-3440-5108
Henrik HasleDepartment of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.ORCID https://orcid.org/0000-0003-3976-9231
Ali AmidiUnit for Psychooncology & Health Psychology, Department of Psychology and Behavioural Sciences, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0003-2921-9797
Aarhus University · DKAarhus University Hospital · DKDanish Cancer Society · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Childhood brain tumor survivors are at high risk of late effects, especially neurocognitive impairment. Limited data are available examining neurocognitive function and associations with quality of life (QoL) in childhood brain tumor survivors. Our aim was to examine neurocognitive function in childhood brain tumor survivors, and associations with QoL and symptom burden. Methods: Five-year survivors of brain tumors over the age of 15 were identified in the Danish Childhood Cancer Registry ( Results: In total, 170 survivors participated (40.2% participation rate). Sixty-six percent of the survivors who completed neurocognitive tests ( Conclusions: In this study, a majority of the childhood brain tumor survivors experienced neurocognitive impairment, reduced QoL, and high symptom burden. Although not associated with each other, it is apparent that childhood brain tumor survivors experience not only neurocognitive dysfunction but may also experience QoL impairments and significant symptom burden.

Indexed as

childhood brain tumor survivorshealth-related quality of lifeneurocognitionsymptom burden

Identifiers

PMID36970169
PMCPMC10037941
OpenAlexW4307381613

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.