Evidence map›Paper›PMID 36970127›Full record

ArticleResearch and practice in thrombosis and haemostasis2023

Autoimmune disease and risk of postpartum venous thromboembolism.

Rob F Walker, Neil A Zakai, Susan M Mason, Richard F MacLehose, Faye L Norby, Line H Evensen, Alvaro Alonso, Pamela L Lutsey

Open access · goldFull text read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Rob F WalkerSchool of Public Health, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Neil A ZakaiDepartment of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA.
Susan M MasonSchool of Public Health, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Richard F MacLehoseSchool of Public Health, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
Faye L NorbyDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, California, USA.
Line H EvensenK.G. Jebsen - Thrombosis Research and Expertise Center, Department of Clinical Medicine, UiT-The Arctic University of Norway, Tromsø, Norway.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Pamela L LutseySchool of Public Health, Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.
University of Minnesota · USCedars-Sinai Smidt Heart Institute · USEmory University · USUiT The Arctic University of Norway · NOUniversity of Vermont · US

Funding

Sudden Death Associated with Substance UseK01HL164764 · NHLBI · UNIVERSITY OF MINNESOTA · PI Faye Norby · 2022 to 2026
$706k
Mentoring and Research in Patient-Oriented Cardiovascular PharmacoepidemiologyK24HL159246 · NHLBI · UNIVERSITY OF MINNESOTA · PI PAMELA L. Lutsey · 2021 to 2026
$644k
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
NHLBI NIH HHS K01 HL164764NHLBI NIH HHS K24 HL148521NHLBI NIH HHS K24 HL159246
6 · The paper itself

Abstract

Background: The risk of pregnancy-related mortality in the United States has nearly doubled since 1990, with venous thromboembolism (VTE) accounting for approximately 10% of these deaths. Objectives: The objective of this study was to assess whether preexisting autoimmune disease is a risk factor for postpartum VTE. Methods: Using the MarketScan Commercial and Medicare Supplemental administrative databases, a retrospective cohort study analyzed whether postpartum persons with autoimmune disease had a higher risk of postpartum VTE incidence than postpartum persons without autoimmune disease. Using International Classification of Diseases codes, we identified 757,303 individuals of childbearing age who had a valid delivery date with at least 12 weeks of follow-up. Results: Individuals were, on average, 30.7 years old (SD, 5.4), and 3.7% ( Conclusion: Autoimmune disease was associated with a higher rate of postpartum VTE, with evidence that the association was most pronounced among individuals with systemic lupus erythematosus and Crohn's disease. These findings suggest that postpartum persons of childbearing age with autoimmune disease may require more monitoring and prophylactic care after delivery to prevent potentially fatal VTE events.

Indexed as

autoimmune diseasespostpartum periodpregnancysystemic lupus erythematosusvenous thromboembolism

Identifiers

PMID36970127
PMCPMC10031534
OpenAlexW4321601983

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read40
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.