Evidence map›Paper›PMID 36970123›Full record

ArticleNature aging2021

Using 'Big Data' to Disentangle Aging and COVID-19.

Ruth R Montgomery, Hanno Steen

Abstract readComment
In one paragraph

Article in Nature aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Immune ageing at single-cell resolution.Nature reviews. Immunology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ruth R MontgomeryDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT.
Hanno SteenDepartment of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA; Precision Vaccines Program, Boston Children's Hospital, Boston, MA.

Funding

Systems investigation of vaccine responses in B cell depleted autoimmune patientsU19AI089992 · NIAID · YALE UNIVERSITY · PI David A. Hafler, RUTH R MONTGOMERY · 2010 to 2026
$50.4M
Transcriptomics to define biomarkers of neonatal vaccine immunogenicityU19AI118608 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI OZONOFF, AL · 2017 to 2021
$24.7M
High-throughput proteomics using submicroliter amounts of plasma for comprehensive assessment of the immune statusU24AI152179 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI STEEN, HANNO · 2020 to 2024
$6.3M
The Impact of HIV Infection on Immunologic, Transcriptomic, and Metabolomic Signatures of Medication-Assisted Therapy for Opioid AddictionR01DA043337 · NIDA · YALE UNIVERSITY · PI SHAW, ALBERT C, SPRINGER, SANDRA ANN · 2016 to 2020
$5.8M
The Impact of Aging and HIV Infection on Immunologic and Transcriptomic Signatures of Influenza Vaccine ResponseR01AG055362 · NIA · YALE UNIVERSITY · PI KANG, INSOO, SHAW, ALBERT C · 2017 to 2021
$4.0M
Integrated Platform to study Neurodegeneration in Alzheimer’s DiseaseR01AG071858 · NIA · BOSTON CHILDREN'S HOSPITAL · PI STEEN, JUDITH A · 2021 to 2025
$3.9M
Circadian Rhythms and Innate Immune Response in AgingR01AI142624 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL, SHAW, ALBERT C · 2019 to 2023
$2.4M
The role of NLRP6 and DHX15 in control of infection by RNA virusesR01AI127865 · NIAID · YALE UNIVERSITY · PI FIKRIG, EROL, FLAVELL, RICHARD A · 2018 to 2022
$2.1M
NIAID NIH HHS R01 AI127865NIAID NIH HHS R01 AI142624NIAID NIH HHS U19 AI089992NIAID NIH HHS U19 AI118608NIAID NIH HHS U24 AI152179NIA NIH HHS R01 AG055362NIA NIH HHS R01 AG071858NIDA NIH HHS R01 DA043337
6 · The paper itself

Abstract

Arthur

Indexed as

COVID-19Healthy AgingArchivesBig DataHumansProteomics

Identifiers

PMID36970123
PMCPMC10035541

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.