Evidence map›Paper›PMID 36969984›Full record

ArticleCardiology discovery2023

Effect of D

Duofen He, Hongmei Ren, Hongyong Wang, Pedro A Jose, Chunyu Zeng, Tianyang Xia, Jian Yang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiology discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The salt sensitivity of Drd4-null mice is associated with the upregulations of sodium transporters in kidneys.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Duofen HeDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Hongmei RenDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Hongyong WangDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Pedro A JoseDivision of Renal Diseases & Hypertension, Department of Medicine and Department of Physiology and Pharmacology, The George Washington University School of Medicine & Health Sciences, Washington, District of Columbia 20052, USA.
Chunyu ZengDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Tianyang XiaDepartment of Cardiology, Daping Hospital, The Third Military Medical University, Chongqing 400042, China.
Jian YangResearch Center for Metabolic and Cardiovascular Diseases, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 410020, China.
Daping Hospital · CNArmy Medical University · CNFirst Affiliated Hospital of Chongqing Medical University · CNGeorge Washington University · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GILDEA, JOHN JOSEPH · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
NHLBI NIH HHS P01 HL074940NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK119652
6 · The paper itself

Abstract

Dopamine, via its receptors, plays a vital role in the maintenance of blood pressure by modulating renal sodium transport. However, the role of the D Methods: NKA activity, nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) levels were measured in RPT cells treated with the D Results: Activation of D Conclusions: Activation of D

Indexed as

Dopamine D4 receptorHypertensionKidneyRenal proximal tubuleSodium-potassium-exchanging ATPase

Identifiers

PMID36969984
PMCPMC10030170
OpenAlexW2367134736

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.