Evidence map›Paper›PMID 36969703›Full record

ArticleAtherosclerosis plus2023

Dyslipidemia and the preventive potential in the Greenlandic population.

Johan Skov Bundgaard, Marit E Jørgensen, Kristine Andersen, Henning Bundgaard, Uka Wilhjelm Geisler, Michael Lynge Pedersen

Open access · goldAbstract read
In one paragraph

Article in Atherosclerosis plus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Genetic determinants of plasma lipids in Greenlanders.Current opinion in lipidology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Johan Skov BundgaardQueen Ingrid Primary Health Care Centre, Nuuk, Greenland.
Marit E JørgensenSteno Diabetes Center Greenland, Nuuk, Greenland.
Kristine AndersenGreenland Centre of Health Research, Institute of Health and Nature, University of Greenland, Nuuk, Greenland.
Henning BundgaardDepartment of Cardiology, The Heart Center, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Uka Wilhjelm GeislerDepartment of Internal Medicine, Queen Ingrid Hospital, Nuuk, Greenland.
Michael Lynge PedersenQueen Ingrid Primary Health Care Centre, Nuuk, Greenland.
Ilisimatusarfik · GLCopenhagen University Hospital · DKQueen Ingrid's Hospital · GL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Low-density lipoprotein cholesterol (LDL-C) is a well-established risk factor for development of cardiovascular diseases. Based on available clinical data, we aimed to investigate the plasma lipid profile in the Greenlandic population, the proportion on cholesterol-lowering treatment and the adherence to local indications for cholesterol-lowering therapy. Methods: This is an observational cross-sectional study of the adult (≥21 years) Greenlandic population with focus on clinically determined lipid levels from 2017 to early 2022. We investigated levels of dyslipidemia and assessed cholesterol-lowering medication usage in individuals with an indication according to current Greenlandic guidelines, which include a) LDL-C >5 mmol/l, b) diabetes, c) diagnosed atherosclerotic disease and 4) a SCORE2 >7.5%. Results: In the adult Greenlandic population of 40,565 individuals a lipid profile was available in 13,895 with a mean LDL-C of 3.0 mmol/L and 976 (7%) had a LDL-C >5 mmol/l. One or more indications for cholesterol-lowering medication was present in 3988 individuals and a total of 5464 adult Greenlanders either fulfilled local criteria for statin therapy or received a statin (some without current indication) and among these, 2232 (41%) individuals received no statin. Conclusion: These findings indicate that clinically significant dyslipidemia is common in the adult Greenlandic population and that the cardiovascular preventive potential of cholesterol-lowering therapy is currently underutilized.

Indexed as

Arctic healthCholesterolEpidemiologyPlasma lipidStatins

Identifiers

PMID36969703
PMCPMC10037086
OpenAlexW4312208420

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.