Evidence map›Paper›PMID 36969559›Full record

ArticleJournal of early intervention2023

Toddlers at Elevated Likelihood for Autism: Exploring Sensory and Language Treatment Predictors.

Alapika Jatkar, Dunia Garrido, Shuting Zheng, Greyson Silverman, Heba Elsayed, Paige Huguely Davis, Helen Lee, Elizabeth R Crais, John Sideris, Lauren Turner-Brown and 3 more

Abstract read
In one paragraph

Article in Journal of early intervention, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alapika JatkarThe University of North Carolina at Chapel Hill, Carolina Institute for Developmental Disabilities, Chapel Hill, NC, USA.ORCID 0000-0001-6899-736X
Dunia GarridoThe University of Granada, Mind, Brain, and Behaviors Research Center, Granada, Spain.
Shuting ZhengThe University of California at San Francisco, San Francisco, CA, USA.
Greyson SilvermanThe University of North Carolina at Chapel Hill, Division of Speech and Hearing Sciences, Chapel Hill, NC, USA.
Heba ElsayedThe University of North Carolina at Chapel Hill, Division of Speech and Hearing Sciences, Chapel Hill, NC, USA.
Paige Huguely DavisThe University of North Carolina at Chapel Hill, Carolina Institute for Developmental Disabilities, Chapel Hill, NC, USA.
Helen LeeThe University of Southern California, Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy, Los Angeles, CA, USA.
Elizabeth R CraisThe University of North Carolina at Chapel Hill, Division of Speech and Hearing Sciences, Chapel Hill, NC, USA.
John SiderisThe University of Southern California, Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy, Los Angeles, CA, USA.
Lauren Turner-BrownThe University of North Carolina at Chapel Hill, Department of Psychiatry, Chapel Hill, NC, USA.
Grace T BaranekThe University of Southern California, Mrs. T.H. Chan Division of Occupational Science and Occupational Therapy, Los Angeles, CA, USA.ORCID 0000-0002-5321-6353
Linda R WatsonThe University of North Carolina at Chapel Hill, Division of Speech and Hearing Sciences, Chapel Hill, NC, USA.
Rebecca GrzadzinskiThe University of North Carolina at Chapel Hill, Carolina Institute for Developmental Disabilities, Chapel Hill, NC, USA.

Funding

North Carolina Translational and Clinical Science Institute (NC TraCS) KL2KL2TR002490 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WEINBERGER, MORRIS · 2018 to 2022
$11.0M
Postdoctoral Research in Neurodevelopmental DisordersT32HD040127 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BENJAMIN D PHILPOT, Mark D Shen · 2001 to 2026
$8.5M
NCATS NIH HHS KL2 TR002490NICHD NIH HHS L30 HD099884NICHD NIH HHS T32 HD040127
6 · The paper itself

Abstract

Baseline child characteristics may predict treatment outcomes in children with or at elevated likelihood of developing autism (EL-ASD). Little is known about the role of child sensory and language features on treatment outcome. Participants were randomly assigned to a parent-mediated intervention or control condition. Analyses explored the relationship between baseline child sensory and language characteristics and changes in ASD symptoms over approximately 9 months. Higher baseline sensory hyporeactivity was significantly related to less improvement in social communication (SC) for the treatment group only. More baseline atypical vocalizations were significantly related to less improvement on SC across treatment and control groups. This work provides an initial framework to encourage the tailoring of interventions for EL-ASD children, suggesting sensory reactivity and atypical vocalizations may be useful behaviors to consider in treatment planning.

Indexed as

autism spectrum disorderschild developmentdisabilities and development delaysinfants and toddlerslanguage and communicationyoung children

Identifiers

PMID36969559
PMCPMC10038203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.