Evidence map›Paper›PMID 36969499›Full record

ArticleTherapeutic advances in urology

Cytomegalovirus haemorrhagic cystitis in a pregnant patient with AIDS.

Bernard Marais, Veena John, Mariëtte Du Toit, Jeanne Mbambo, Jeff John

Abstract readCase Reports
In one paragraph

Article in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bernard MaraisDepartment of Urology, Frere Hospital, Walter Sisulu University, East London 5200, South Africa.ORCID https://orcid.org/0000-0003-0637-0339
Veena JohnDepartment of Paediatrics, Frere Hospital, Walter Sisulu University, East London, South Africa.ORCID https://orcid.org/0000-0002-2645-8891
Mariëtte Du ToitDivision of Anatomical Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Jeanne MbamboDepartment of Urology, Frere Hospital, Walter Sisulu University, East London, South Africa.
Jeff JohnDepartment of Urology, Frere Hospital, Walter Sisulu University, East London, South Africa.ORCID https://orcid.org/0000-0002-6139-810X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV), an AIDS defining disease, has a high seroprevalence in the general population, while symptomatic infections occur mostly in immunocompromised individuals. Symptomatic CMV infections commonly include pneumonia, encephalitis, retinitis and colitis, while urinary tract involvement is a rare entity. We present a rare case of massive macroscopic haematuria due to CMV haemorrhagic cystitis in a 29-year-old woman in her second trimester of pregnancy. She was treated with intravenous Ganciclovir after initial resuscitation, and her symptoms promptly resolved. Timely diagnosis and treatment of symptomatic CMV infection is necessary to prevent associated morbidity, and this is especially significant during pregnancy in order to prevent foetal transmission. Both our patient and her baby remained symptom free at the 6-month follow-up post-delivery. Clinicians should have a high index of suspicion to biopsy the bladder urothelium of at-risk patients who present with haemorrhagic cystitis and have non-specific cystoscopy findings as histopathological analysis is the mainstay of diagnosing CMV-cystitis.

Indexed as

AIDScytomegalovirushaematuriahaemorrhagic cystitisimmunodeficiencypregnancy

Identifiers

PMID36969499
PMCPMC10034270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.