Evidence map›Paper›PMID 36969350›Full record

ReviewAvicenna journal of medicine2023

A Clinical Overview of Anorexia Nervosa and Overcoming Treatment Resistance.

Hassan Nagy, Tanya Paul, Esha Jain, Hanyou Loh, Syeda Hafsa Kazmi, Rishbha Dua, Ricardo Rodriguez, Syed Ali Abbas Naqvi, Metu Chiamaka U, Erjola Bidika

Full text readReview
In one paragraph

Review in Avicenna journal of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hassan NagyDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0001-9589-1333
Tanya PaulDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0002-2532-0196
Esha JainDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0002-6618-8187
Hanyou LohDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0002-9085-8582
Syeda Hafsa KazmiDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0003-0007-124X
Rishbha DuaDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0001-7758-775X
Ricardo RodriguezDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0002-2216-0975
Syed Ali Abbas NaqviDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0003-4254-6565
Metu Chiamaka UDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0001-6721-6752
Erjola BidikaDivision of Research & Academic Affairs, Larkin Health System, South, Miami, Florida, United States.ORCID 0000-0001-5630-4642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anorexia nervosa (AN) is a type of eating disorder that has been increasing in incidence and has been encountered more commonly by physicians in their daily practice. Both environmental and genetic risk factors paired along with a more susceptible neurobiology are at play in the emerging resistance to treatment in AN. Preoccupations with intense fear of weight gain, dietary restrictions, excessive exercise, and how the individual is perceived by society mixed with underlying psychopathology all further add to the issue. Many patients who fall into this cycle of obsessive and restrictive patterns refuse to get treatment. As clinicians, it is essential we recognize the early signs of both eating disorders during the initial primary care appointments. To review the literature on the etiology of AN, possible misdiagnosis leading to inappropriate management of this condition, and understand the treatment-resistant AN and its management. Additionally, it will explore possible reasons that contribute to the resistance to treatment, the underlying psychopathology of anorexics, its genetic predisposition, psychiatric comorbidities, identification of the early signs and symptoms, and timely prevention. Early recognition by a physician includes a thorough history and physical examination, pertinent laboratory, and electrolyte studies, and identifying comorbid psychiatric conditions. The treatment of AN is intricate and requires a holistic approach. Treatment includes multiple modalities such as nutritional rehabilitation and psychosocial and pharmacological therapies. An interdisciplinary team of medical professionals for managing chronic AN is recommended.

Indexed as

anorexia nervosadeep brain stimulation in anorexicseating disordersmanaging chronic anorexiapsychiatric disorderspsychosocial treatments of anorexiatreatment-resistant anorexia

Identifiers

PMID36969350
PMCPMC10038755

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.