Evidence map›Paper›PMID 36969151›Full record

ArticleFrontiers in immunology2023

Next-generation humanized NSG-SGM3 mice are highly susceptible to

Sophia Hung, Amelie Kasperkowitz, Florian Kurz, Liane Dreher, Joachim Diessner, Eslam S Ibrahim, Stefan Schwarz, Knut Ohlsen, Tobias Hertlein

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Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Pre-clinical strategies and emerging technologies driving advances in the alpha-gal syndrome.Allergology international : official journal of the Japanese Society of Allergology · 2025
    Review
  2. Article
  3. Review
  4. Immune Checkpoint Molecules as Biomarkers ofbioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Humanized Mouse Models of Bacterial Infections.Antibiotics (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sophia HungInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Amelie KasperkowitzInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Florian KurzInstitute of Pathology, University of Würzburg, Würzburg, Germany.
Liane DreherInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Joachim DiessnerDepartment for Obstetrics and Gynecology, University Hospital of Würzburg, Würzburg, Germany.
Eslam S IbrahimInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Stefan SchwarzInstitute of Microbiology and Epizootics, Centre for Infection Medicine, School of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
Knut OhlsenInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Tobias HertleinInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humanized hemato-lymphoid system mice, or humanized mice, emerged in recent years as a promising model to study the course of infection of human-adapted or human-specific pathogens. Though

Indexed as

Staphylococcal InfectionsStaphylococcus aureusAnimalsCytokinesHumansMiceMice, Inbred NODMice, KnockoutNeutrophilsCytokineshumanized hemato-lymphoid micehumanized miceMRSANSGNSG-SGM3staphylococcal abscessStaphylococcus aureusStaphylococcus aureus immune response

Identifiers

PMID36969151
PMCPMC10037040

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.