ArticleFrontiers in oncology2023
Squamous cell carcinoma of ascending colon with pMMR/MSS showed a partial response to PD-1 blockade combined with chemotherapy: A case report.
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 9 citations in OpenAlex.
- Diet-Driven Epigenetic Alterations in Colorectal Cancer: From DNA Methylation and microRNA Expression to Liquid Biopsy Readouts.Biomedicines · 2026Review
- Pathological complete response following immunotherapy in dMMR/MSI-H ascending colon primary squamous cell carcinoma: a case report.Frontiers in immunology · 2026Article
- The enigma of squamous cell carcinoma of the colon: a case report and review.Frontiers in oncology · 2026Review
- Postpartum colonic squamous cell carcinoma with a BRAFJournal of medical case reports · 2025Article
- Primary squamous cell carcinoma of the descending colon with pancreatic metastasis: A case report.World journal of gastrointestinal oncology · 2025Article
- An unexpected primary squamous cell carcinoma of the left colon: a rare case report.Journal of surgical case reports · 2024Article
- Case Report: A management strategy and clinical analysis of primary squamous cell carcinoma of the colon.Frontiers in oncology · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Primary colon squamous cell carcinoma (SCC) is extremely rare and associated with a poor prognosis. Moreover, there is no treatment guideline for this disease. Proficient mismatch repair/microsatellite-stable (pMMR/MSS) colorectal adenocarcinoma is refractory to immune monotherapy. Although the combination of immunotherapy with chemotherapy in pMMR/MSS colorectal cancer (CRC) is currently under investigation, the clinical activity of this approach in colorectal SCC remains unknown. In this article, we report the case of a pMMR/MSS CRC patient with ascending colon SCC who had high programmed cell death-ligand 1 (PD-L1) expression and the a missense mutation in codon 600 of the B-Raf proto-oncogene (BRAF
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