Evidence map›Paper›PMID 36969002›Full record

ReviewFrontiers in oncology2023

Immune cells and immune cell-targeted therapy in chronic pancreatitis.

Yu Zhang, Wen-Qing Zhang, Xin-Yuan Liu, Qi Zhang, Tao Mao, Xiao-Yu Li

Open access · goldFull text readReview
In one paragraph

Review in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yu ZhangDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wen-Qing ZhangDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xin-Yuan LiuDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qi ZhangDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Tao MaoDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiao-Yu LiDepartment of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, studies have attempted to understand the immune cells and mechanisms underlying the pathogenesis of chronic pancreatitis (CP) by constructing a model of CP. Based on these studies, the innate immune response is a key factor in disease pathogenesis and inflammation severity. Novel mechanisms of crosstalk between immune and non-immune pancreatic cells, such as pancreatic stellate cells (PSC), have also been explored. Immune cells, immune responses, and signaling pathways in CP are important factors in the development and progression of pancreatitis. Based on these mechanisms, targeted therapy may provide a feasible scheme to stop or reverse the progression of the disease in the future and provide a new direction for the treatment of CP. This review summarizes the recent advances in research on immune mechanisms in CP and the new advances in treatment based on these mechanisms.

Indexed as

chronic pancreatitisimmunotherapymacrophagepancreatic stellate cellsT cell

Identifiers

PMID36969002
PMCPMC10034053
OpenAlexW4323665834

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read32
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.