Evidence map›Paper›PMID 36968957›Full record

ArticleOpen forum infectious diseases2023

Predictors of Human Immunodeficiency Virus Pre-Exposure Prophylaxis (PrEP) Uptake in a Sexual Health Clinic With Rapid PrEP Initiation.

Gabriel A Wagner, Kuan-Sheng Wu, Christy Anderson, Alina Burgi, Susan J Little

Registry-linked trialAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06159582 (eSTEP), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06159582 nacompletednot on this mapstarted 2024, after this paper: background citation

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

TypeinterventionalSponsorSan Diego State UniversityRan2024 to 2025Enrolled113ConditionsPre-Exposure Prophylaxis (PrEP)ArmseSTEP, Usual Care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel A WagnerDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California, USA.
Kuan-Sheng WuDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California, USA.
Christy AndersonDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California, USA.
Alina BurgiDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California, USA.
Susan J LittleDivision of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, San Diego, California, USA.

Funding

Primary Infection Resource Consortium (PIRC)R24AI106039 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2013 to 2021
$23.1M
Efficacy of ART to Interrupt HIV Transmission NetworksR01MH100974 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LITTLE, SUSAN JANET · 2014 to 2018
$3.2M
HIV-1 Dual Infection and Neurocognitive Impairment.K23MH105231 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WAGNER, GABRIEL ARTURO · 2016 to 2019
$813k
NIAID NIH HHS R24 AI106039NIMH NIH HHS K23 MH105231NIMH NIH HHS R01 MH100974
6 · The paper itself

Abstract

Background: Improved pre-exposure prophylaxis (PrEP) uptake is essential for human immunodeficiency virus (HIV) prevention initiatives. Offering PrEP at the time of HIV and sexually transmitted infection (STI) testing can improve uptake. We offered rapid PrEP initiation in a sexual health clinic and assessed predictors of PrEP interest, initiation, linkage, and retention. Methods: Between November 2018 and February 2020, PrEP-eligible individuals who presented to a sexual health clinic were offered a free 30-day supply of PrEP plus linkage to continued PrEP care. Univariable and multivariable analyses of demographic and HIV risk data were conducted to determine predictors of PrEP uptake. Results: Of 1259 adults who were eligible for PrEP (99.7% male, 42.7% White, 36.2% Hispanic), 456 were interested in PrEP, 249 initiated PrEP, 209 were linked, and 67 were retained in care. Predictors of PrEP interest included younger age ( Conclusions: A minority of PrEP-eligible HIV and STI testers initiated PrEP when offered, suggesting that easy PrEP access in sexual health clinics alone may not improve uptake. Predictors of uptake included established HIV risk factors and markers of higher socioeconomic status, suggesting that those aware of their risk and with the means to utilize health services engaged best with this model.

Indexed as

HIV preventionrapid prEP

Identifiers

PMID36968957
PMCPMC10034584

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.