Evidence map›Paper›PMID 36968875›Full record

ReviewCureus2023

A Meta-Analysis on Predictors of Mortality Among Patients Hospitalized for Acute Exacerbation of Asthma.

Abdulmaleek Idanesimhe Sado, Muhammad S Afzal, Lavanya Kannekanti, Hrushikesh Reddy Pamreddy, Jorge Pimentel Campillo, Vaishnavi Kandukuri, Gnana Deepthi Medarametla, Sujith K Palleti

Full text readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mapping the Burden of Fungal Diseases in the United Arab Emirates.Journal of fungi (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdulmaleek Idanesimhe SadoDepartment of Medicine, Penwortham St Mary's Medical Group, Preston, GBR.
Muhammad S AfzalDepartment of Medicine, Carle Foundation Hospital, Urbana, USA.
Lavanya KannekantiDepartment of Medicine, Osmania Medical College, Hyderabad, IND.
Hrushikesh Reddy PamreddyDepartment of Internal Medicine, Osmania Medical College, Hyderabad, IND.
Jorge Pimentel CampilloDepartment of Internal Medicine, CEDIMAT, Santo Domingo, DOM.
Vaishnavi KandukuriDepartment of Internal Medicine, Gandhi Medical College and Hospital, Hyderabad, IND.
Gnana Deepthi MedarametlaDepartment of Internal Medicine, NRI Medical College and Hospital, Guntur, IND.
Sujith K PalletiDepartment of Nephrology, Edward Hines Jr. Veterans Administration Hospital, Hines, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this meta-analysis is to systematically review published studies and identify clinically important factors predicting mortality among patients hospitalized for acute exacerbation of asthma. This study was a meta-analysis conducted in accordance with the MOOSE (Meta-analysis of Observational Studies in Epidemiology) guidelines. A systematic search was carried out on online databases such as PubMed and EMBASE to identify articles on predictors of mortality among patients hospitalized for acute exacerbation of asthma. The search used keywords such as "asthma," "exacerbation," "mortality," and "factors." A total of six articles met the inclusion criteria and were included in the present meta-analysis. The incidence of short-term mortality among patients hospitalized for acute exacerbation of asthma was 6% (95% CI= 3-9%, I-square=99%) with a range of 0.79% to 18% across the studies. The factors significantly associated with short-term mortality in patients hospitalized for acute exacerbation of asthma including diabetes mellitus (RR=2.02, 95% CI: 1.63-2.52, p-value=0.001), pneumonia (RR=3.71, 95% CI: 3.02-4.56, p-value=0.001), and mechanical ventilation (RR: 29.98, 95% CI: 15.46-58.15, p-value=0.001). The present study found that diabetes mellitus, pneumonia, and the use of mechanical ventilation are independently associated with mortality among patients hospitalized for acute exacerbation of asthma. Healthcare professionals need to understand the comorbidities and risk factors associated with mortality in patients hospitalized for acute exacerbation of asthma in order to identify patients who are at increased risk and provide prompt treatment.

Indexed as

asthmaexacerbationmeta-analysismortalitypredictors

Identifiers

PMID36968875
PMCPMC10032559

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.