Evidence map›Paper›PMID 36968792›Full record

ArticleNano today2022

On-Demand Synthesis of Antiseptics at the Site of Infection for Treatment of Otitis Media.

Jiayan Lang, Xiaojing Ma, Sophie S Liu, Danielle L Streever, Max D Serota, Trevor Franklin, Ellis R Loew, Rong Yang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nano today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jiayan LangRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Xiaojing MaRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Sophie S LiuRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Danielle L StreeverMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.
Max D SerotaRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Trevor FranklinRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Ellis R LoewCollege of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
Rong YangRobert F. Smith School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Cornell University · US

Funding

Trans-Tympanic Drug Delivery for Treatment and Prophylaxis of Otitis MediaR00DC016644 · NIDCD · CORNELL UNIVERSITY · PI YANG, RONG · 2019 to 2021
$734k
NIDCD NIH HHS R00 DC016644
6 · The paper itself

Abstract

Otitis media (OM) is the main reason for pediatric antibiotic prescriptions. The current treatment mandates a rigorous regimen of multidose antibiotics over 5-10 days. The systemic antibiotic exposure and often prematurely terminated treatment due to the challenge of drug administration to young patients are believed to breed antibiotic resistance. To address these challenges, we designed a local treatment that converted a metabolic product (H

Indexed as

antisepticshaloperoxidase-like activityon-demand synthesisotitis mediaVanadium pentoxide nanowire

Identifiers

PMID36968792
PMCPMC10035358
OpenAlexW4309194040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.