Evidence map›Paper›PMID 36968708›Full record

ArticleFrontiers in psychology2023

Mindfulness skills and experiential avoidance as therapeutic mechanisms for treatment-resistant depression through mindfulness-based cognitive therapy and lifestyle modification.

Mauro Garcia-Toro, Alejandra Aguilar-Latorre, Aurora Garcia, Capilla Navarro-Guzmán, Elena Gervilla, Andrea Seguí, Francisco Gazquez, Jose Antonio Marino, Rocío Gomez-Juanes, María J Serrano-Ripoll and 4 more

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Article in Frontiers in psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mauro Garcia-ToroUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
Alejandra Aguilar-LatorreResearch Network on Chronicity, Primary Care and Health Promotion (RICAPPS), Carlos III Health Institute, Madrid, Spain.
Aurora GarciaUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
Capilla Navarro-GuzmánDepartment of Psychology, University of the Balearic Islands, Palma, Spain.
Elena GervillaHealth Research Institute of the Balearic Islands (IdISBa), Palma, Spain.
Andrea SeguíUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
Francisco GazquezUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
Jose Antonio MarinoUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
Rocío Gomez-JuanesUniversity Institute of Health Science Research (IUNICS), University of the Balearic Islands, Palma, Spain.
María J Serrano-RipollHealth Research Institute of the Balearic Islands (IdISBa), Palma, Spain.
Bárbara Oliván-BlázquezResearch Network on Chronicity, Primary Care and Health Promotion (RICAPPS), Carlos III Health Institute, Madrid, Spain.
Javier Garcia-CampayoResearch Network on Chronicity, Primary Care and Health Promotion (RICAPPS), Carlos III Health Institute, Madrid, Spain.
Shannon MaloneyDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.
Jesús Montero-MarinDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/objective: The COVID-19 pandemic and consequent physical distancing has made it difficult to provide care for those with Treatment-Resistant Depression (TRD). As a secondary analysis of a clinical trial, the aim of this study was to explore potential mechanisms through which three online-delivered approaches, added to treatment as usual, improve depressive symptoms in TRD patients. Methods: The three approaches included (a) Minimal Lifestyle Intervention (MLI), (b) Mindfulness-Based Cognitive Therapy (MBCT), and (c) Lifestyle Modification Program (LMP). Sixty-six participants with TRD completed assessments pre-post intervention (mindfulness skills [FFMQ]; self-compassion [SCS]; and experiential avoidance [AAQ-II]) and pre-intervention to follow-up (depressive symptoms [BDI-II]). Data were analyzed using within-subjects regression models to test mediation. Results: Mindfulness skills mediated the effect of MBCT on depressive symptoms ( Conclusion: Strengthening mindfulness skills and decreasing experiential avoidance may promote recovery in patients with TRD, MBCT, and LMP have demonstrated that they may help increase mindfulness skills and decrease experiential avoidance, respectively. Future work will need to unpick the components of these interventions to help isolate active ingredients and increase optimization.

Indexed as

interventionlifestyle modificationmajor depressive disorderMBCTmediation

Identifiers

PMID36968708
PMCPMC10033944

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.