Evidence map›Paper›PMID 36968638›Full record

ArticleAnnual review of statistics and its application2023

High-Dimensional Survival Analysis: Methods and Applications.

Stephen Salerno, Yi Li

Abstract read
In one paragraph

Article in Annual review of statistics and its application, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. A CLRN3-Based CD8Biomolecules · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen SalernoDepartment of Biostatistics, University of Michigan, Ann Arbor, United States, 48109.
Yi LiDepartment of Biostatistics, University of Michigan, Ann Arbor, United States, 48109.

Funding

New Statistical Methods for Modelling Cancer OutcomesR01CA249096 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Yi Li · 2021 to 2026
$2.5M
NCI NIH HHS R01 CA249096
6 · The paper itself

Abstract

In the era of precision medicine, time-to-event outcomes such as time to death or progression are routinely collected, along with high-throughput covariates. These high-dimensional data defy classical survival regression models, which are either infeasible to fit or likely to incur low predictability due to over-fitting. To overcome this, recent emphasis has been placed on developing novel approaches for feature selection and survival prognostication. We will review various cutting-edge methods that handle survival outcome data with high-dimensional predictors, highlighting recent innovations in machine learning approaches for survival prediction. We will cover the statistical intuitions and principles behind these methods and conclude with extensions to more complex settings, where competing events are observed. We exemplify these methods with applications to the Boston Lung Cancer Survival Cohort study, one of the largest cancer epidemiology cohorts investigating the complex mechanisms of lung cancer.

Indexed as

artificial neural networkdata sciencefeature screeningmachine learningprecision medicinestatistical inference

Identifiers

PMID36968638
PMCPMC10038209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.