Evidence map›Paper›PMID 36968621›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Establishing cognitive baseline in three generations: Framingham Heart Study.

Jin Yang, Ting Fang Alvin Ang, Sophia Lu, Xue Liu, Sherral Devine, Rhoda Au, Chunyu Liu

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. AI-based differential diagnosis of dementia etiologies on multimodal data.medRxiv : the preprint server for health sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jin YangDepartment for Endemic Disease Control and Prevention Henan Provincial Center for Disease Control and Prevention Zhengzhou China.
Ting Fang Alvin AngDepartment of Anatomy and Neurobiology Boston University School of Medicine Boston Massachusetts USA.
Sophia LuDepartment of Biostatistics Boston University School of Public Health Boston Massachusetts USA.
Xue LiuDepartment of Biostatistics Boston University School of Public Health Boston Massachusetts USA.
Sherral DevineDepartment of Anatomy and Neurobiology Boston University School of Medicine Boston Massachusetts USA.
Rhoda AuDepartment of Anatomy and Neurobiology Boston University School of Medicine Boston Massachusetts USA.
Chunyu LiuFramingham Heart Study Boston University School of Medicine Boston Massachusetts USA.
Boston University · USFramingham Heart Study · USHenan Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Generational changes warrant recalibrating normative cognitive measures to detect changes indicative of dementia risk within each generation. Methods: We performed linear regressions to compare eight neuropsychological (NP) tests among three-generation cohorts at baseline in Framingham Heart Study (FHS, Results: The FHS second and third generations performed better than the first generation for seven NP tests (0.14-0.81 standard deviation improvement, Discussion: Our findings suggest cohort-based norms are needed for cognitive assessment for the diagnosis of cognitive impairment and dementia.

Indexed as

Alzheimer's diseasecognitive functiondementianeuropsychological testnorms

Identifiers

PMID36968621
PMCPMC10038074
OpenAlexW4360919950

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.