Evidence map›Paper›PMID 36968385›Full record

ArticleFrontiers in plant science2023

Identification of a pluripotency-inducing small compound, PLU, that induces callus formation

Yuki Nakashima, Yuka Kobayashi, Mizuki Murao, Rika Kato, Hitoshi Endo, Asuka Higo, Rie Iwasaki, Mikiko Kojima, Yumiko Takebayashi, Ayato Sato and 8 more

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In one paragraph

Article in Frontiers in plant science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yuki NakashimaCenter for Gene Research, Nagoya University, Nagoya, Japan.
Yuka KobayashiCenter for Gene Research, Nagoya University, Nagoya, Japan.
Mizuki MuraoCenter for Gene Research, Nagoya University, Nagoya, Japan.
Rika KatoGraduate School of Science, Nagoya University, Nagoya, Japan.
Hitoshi EndoInstitute of Transformative Bio-Molecules, Nagoya University, Nagoya, Japan.
Asuka HigoCenter for Gene Research, Nagoya University, Nagoya, Japan.
Rie IwasakiInstitute of Transformative Bio-Molecules, Nagoya University, Nagoya, Japan.
Mikiko KojimaCenter for Sustainable Resource Science, RIKEN, Yokohama, Japan.
Yumiko TakebayashiCenter for Sustainable Resource Science, RIKEN, Yokohama, Japan.
Ayato SatoInstitute of Transformative Bio-Molecules, Nagoya University, Nagoya, Japan.
Mika NomotoCenter for Gene Research, Nagoya University, Nagoya, Japan.
Hitoshi SakakibaraCenter for Sustainable Resource Science, RIKEN, Yokohama, Japan.
Yasuomi TadaCenter for Gene Research, Nagoya University, Nagoya, Japan.
Kenichiro ItamiGraduate School of Science, Nagoya University, Nagoya, Japan.
Seisuke KimuraDepartment of Industrial Life Sciences, Faculty of Life Science, Kyoto Sangyo University, Kyoto, Japan.
Shinya HagiharaCenter for Sustainable Resource Science, RIKEN, Saitama, Japan.
Keiko U ToriiInstitute of Transformative Bio-Molecules, Nagoya University, Nagoya, Japan.
Naoyuki UchidaCenter for Gene Research, Nagoya University, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants retain the ability to generate a pluripotent tissue called callus by dedifferentiating somatic cells. A pluripotent callus can also be artificially induced by culturing explants with hormone mixtures of auxin and cytokinin, and an entire body can then be regenerated from the callus. Here we identified a pluripotency-inducing small compound, PLU, that induces the formation of callus with tissue regeneration potency without the external application of either auxin or cytokinin. The PLU-induced callus expressed several marker genes related to pluripotency acquisition

Indexed as

Arabidopsis thalianaauxincallusHSP90pluripotencysmall compound

Identifiers

PMID36968385
PMCPMC10030974

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.