Evidence map›Paper›PMID 36968168›Full record

ReviewArchives of rehabilitation research and clinical translation2023

The Effects of Intradialytic Exercise on Key Indices of Sarcopenia in Patients With End-stage Renal Disease: A Systematic Review of Randomized Controlled Trials.

Daniel Pender, Ellen McGowan, Joseph G McVeigh, Ruth McCullagh

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Archives of rehabilitation research and clinical translation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07151742 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Investigation of the Effects of Intradialytic Combined Exercises on Dialysis Parameters and Muscle Oxygenation in Sarcopenic Hemodialysis Patients

TypeinterventionalSponsorIstinye UniversityRan2025 to 2025Enrolled40ConditionsChronic Kidney Disease, Stage 5, SarcopeniaArmsEXERCISE TRAINING WITH OR WITHOUT MEDICATION
NCT07720401 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Supervised Intradialytic Exercise Program on Postural Abnormalities in Maintenance Hemodialysis Patients: A Randomized Controlled Trial

TypeinterventionalSponsorPardis Specialized Wellness InstituteRan2026 to 2026Enrolled98ConditionsEnd-Stage Renal Disease, Hemodialysis ComplicationArmsSupervised Intradialytic Multimodal Exercise Program
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel PenderDiscipline of Physiotherapy, School of Clinical Therapies, College of Medicine and Health, University College Cork, Ireland T12 × 70A.
Ellen McGowanDiscipline of Physiotherapy, School of Clinical Therapies, College of Medicine and Health, University College Cork, Ireland T12 × 70A.
Joseph G McVeighDiscipline of Physiotherapy, School of Clinical Therapies, College of Medicine and Health, University College Cork, Ireland T12 × 70A.
Ruth McCullaghDiscipline of Physiotherapy, School of Clinical Therapies, College of Medicine and Health, University College Cork, Ireland T12 × 70A.
University College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effects of intradialytic exercise (IDE) (exercise performed during dialysis) on sarcopenia and quality of life (QoL) in patients with end-stage renal disease (ESRD). Data Sources: A comprehensive search of 7 electronic databases was performed to identify randomized controlled trials measuring the effects of IDE in adults with ESRD. Searches were limited to the English language. Study Selection: Included studies were randomized controlled trials that measured the effects of IDE in adults with ESRD. Comparator groups received usual care or low-intensity sham interventions. Outcomes of interest were muscle mass, strength, physical function, and QoL. Papers were independently screened for eligibility by 2 authors, and any discrepancies resolved by a third author. Data Extraction: One author extracted the data from the included studies. Data were compared and discussed across the team members. Two authors independently assessed risk of bias using the Cochrane Risk of Bias 2 tool. Quality was assessed using the van Tulder scale and a narrative synthesis was conducted. Best evidence synthesis was used to structure the reviews findings. Data Synthesis: Fourteen studies were included in this review (n=837). While risk of bias was found high in 11 studies, demonstrating mainly selection, performance, and detection bias, the best evidence synthesis indicated strong evidence of resistance training improving muscle mass (16%-4.2%) and strength (45%-18%), and moderate evidence of combined exercise improving strength (37%), and various physical function scores. Conclusions: Overall, there is strong evidence of resistance exercise, with moderate evidence of combined exercise, improving sarcopenia-related muscle and strength loss, and QoL in end-stage kidney disease. Adequately powered, good quality studies are required to determine the optimal exercise prescription to maximize outcomes.

Indexed as

ExerciseQuality of lifeRenal dialysisRenal insufficiencySarcopenia

Identifiers

PMID36968168
PMCPMC10036234
OpenAlexW4315864816

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.