Evidence map›Paper›PMID 36968097›Full record

ArticleJournal of experimental nanoscience2022

Impact of administration route on nanocarrier biodistribution in a murine colitis model.

Catherine C Applegate, Hongping Deng, Brittany L Kleszynski, Tzu-Wen L Cross, Christian J Konopka, L Wawrzyniec Dobrucki, Erik R Nelson, Matthew A Wallig, Andrew M Smith, Kelly S Swanson

Open access · goldFull text read
In one paragraph

Article in Journal of experimental nanoscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Catherine C ApplegateDivision of Nutritional Sciences, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Hongping DengDepartment of Bioengineering, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Brittany L KleszynskiDepartment of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Tzu-Wen L CrossDepartment of Nutrition Science, Purdue University, West Lafayette, Indiana, USA.
Christian J KonopkaBeckman Institute for Advanced Science and Technology, Urbana, Illinois, USA.
L Wawrzyniec DobruckiBeckman Institute for Advanced Science and Technology, Urbana, Illinois, USA.
Erik R NelsonDivision of Nutritional Sciences, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Matthew A WalligDivision of Nutritional Sciences, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Andrew M SmithDepartment of Bioengineering, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
Kelly S SwansonDivision of Nutritional Sciences, University of Illinois at Urbana - Champaign, Urbana, Illinois, USA.
University of Illinois Urbana-Champaign · USIllinois College · USPurdue University West Lafayette · US

Funding

Targeted Drug Delivery to Adipose Tissue Macrophages in ObesityR01DK112251 · NIDDK · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SMITH, ANDREW MICHAEL, SWANSON, KELLY S · 2016 to 2020
$2.1M
Impact of cholesterol and its metabolites on breast cancer progressionR01CA234025 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI NELSON, ERIK RUSSELL · 2019 to 2023
$1.7M
NCI NIH HHS R01 CA234025NIDDK NIH HHS R01 DK112251
6 · The paper itself

Abstract

The incidence of inflammatory bowel disease (IBD) is increasing worldwide. Although current diagnostic and disease monitoring tests for IBD sensitively detect gut inflammation, they lack the molecular and cellular specificity of positron emission tomography (PET). In this proof-of-concept study, we use a radiolabeled macrophage-targeted nanocarrier probe (

Indexed as

colitisdextraninflammatory bowel diseasenanoparticlesPET

Identifiers

PMID36968097
PMCPMC10038121
OpenAlexW4306929546

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.