Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors at 1 institution in 1 country.
Nikita TsybaDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Gaomin FengDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN37232, USA.
Lantana K GrubDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
James P HeldDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Adrianna M StrozakDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Kristopher BurkewitzDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN37232, USA.
Maulik R PatelDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Vanderbilt University · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGYT32ES007028 · NIEHS · VANDERBILT UNIVERSITY · PI F PETER Guengerich, Fiona Edith Harrison · 1985 to 2026
$15.7M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanisms of mutant mitochondrial genome modulationR35GM145378 · NIGMS · VANDERBILT UNIVERSITY · PI MAULIK R PATEL · 2022 to 2026
$2.4M
Targeting ER-mitochondrial calcium signaling to promote healthier agingR01AG073354 · NIA · VANDERBILT UNIVERSITY · PI Kristopher Burkewitz · 2022 to 2026
$1.6M
Regulation of mitochondrial heteroplasmy dynamicsR01GM123260 · NIGMS · VANDERBILT UNIVERSITY · PI PATEL, MAULIK R · 2017 to 2021
$1.5M
Unconventional regulation of mTORC1 signaling by inositol phosphate: implications for nutrient-induced premature agingR21AG071975 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLIND, RAYMOND DANIEL, BURKEWITZ, KRISTOPHER · 2022 to 2023
Mutations in the mitochondrial genome (mtDNA) can be pathogenic. Owing to the multi-copy nature of mtDNA, wild-type copies can compensate for the effects of mutant mtDNA. Wild-type copies available for compensation vary depending on the mutant load and the total copy number. Here, we examine both mutant load and copy number in the tissues of
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Tissue-specific heteroplasmy segregation is accompanied by a sharp mtDNA decline in · full record | OpenQuestion