Evidence map›Paper›PMID 36968027›Full record

ArticleRSC advances2023

Electrochemical biosensor based on cellulose nanofibers/graphene oxide and acetylcholinesterase for the detection of chlorpyrifos pesticide in water and fruit juice.

Wonn Shweyi Thet Tun, Apichart Saenchoopa, Sakda Daduang, Jureerat Daduang, Sirinan Kulchat, Rina Patramanon

Abstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wonn Shweyi Thet TunDepartment of Chemistry, Faculty of Science, Khon Kaen University Khon Kaen 40002 Thailand.
Apichart SaenchoopaDepartment of Chemistry, Faculty of Science, Khon Kaen University Khon Kaen 40002 Thailand.
Sakda DaduangFaculty of Pharmaceutical Sciences, Khon Kaen University Khon Kaen 40002 Thailand.
Jureerat DaduangDepartment of Clinical Chemistry, Faculty of Associated Medical Sciences, Khon Kaen University Khon Kaen 40002 Thailand.ORCID https://orcid.org/0000-0003-0977-4144
Sirinan KulchatDepartment of Chemistry, Faculty of Science, Khon Kaen University Khon Kaen 40002 Thailand.ORCID https://orcid.org/0000-0002-2411-7495
Rina PatramanonDepartment of Biochemistry, Faculty of Science, Khon Kaen University Khon Kaen 40002 Thailand narin@kku.ac.th.ORCID https://orcid.org/0000-0002-9325-2527

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, cellulose nanofibers and graphene oxide are used to fabricate a simple and reliable electrochemical biosensor, based on acetylcholinesterase (AChE) for the detection of highly dangerous organophosphates (OPs), utilizing chlorpyrifos as a representative sample. AChE is an enzyme that is essential for neurotransmission and catalyzes the conversion of acetylcholine (ATCh) into thiocholine and acetic acid. The pesticide used in this work, chlorpyrifos, inhibits the catalytic activity of AChE on ATCh, and this inhibition can be measured using square wave voltammetry (SWV). Utilizing a process of surface modification, layers of cellulose nanofibers, graphene oxide, a chitosan-graphene oxide composite, and acetylcholinesterase (AChE/CS-GO/GO/CNFs) were immobilized on a screen-printed carbon electrode (SPCE). The modified SPCE working electrode was characterized using scanning electron microscopy and graphene oxide trapped in the cellulose nanofibers was found to increase the sensitivity of the biosensor. The modified biosensor demonstrated good performance for detection of chlorpyrifos over a linear range of 25-1000 nM under optimum conditions, and the limits of detection and quantification were 2.2 nM and 73 nM, respectively. Our sophisticated technique might offer a more precise, straightforward, quick, and environmentally friendly way to assess chlorpyrifos contamination in water and juice samples.

Identifiers

PMID36968027
PMCPMC10038066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.