Evidence map›Paper›PMID 36967859›Full record

ReviewPostepy w kardiologii interwencyjnej = Advances in interventional cardiology2022

The effect of volatile anesthetics on cellular responses in the microcirculation of free tissue transfers.

Jakub Szrama, Krzysztof Kusza, Paweł Sobczyński, Zsolt Molnar, Maria Siemionow

Abstract readReview
In one paragraph

Review in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jakub SzramaDepartment of Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland.
Krzysztof KuszaChair and Department of Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland.
Paweł SobczyńskiFirst Department of Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland.
Zsolt MolnarDepartment of Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland.
Maria SiemionowUniversity of Illinois, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this review was to summarize the anti-inflammatory and immunosuppressive properties of volatile anesthetics and present their potential impact on the outcomes of major surgical procedures as well as microsurgical cases of free tissue transfer. Inhaled anesthetics are commonly used as a component of general anesthesia in interventional procedures, reconstructive surgery, free tissue transfers and transplantation. Experimental and clinical studies have shown that volatile anesthetics such as halothane, sevoflurane, isoflurane or desflurane can affect the immune system of patients exposed to general anesthesia. In patients with no serious systemic diseases, this effect is transient and mostly clinically irrelevant. However, in patients subjected to the inflammatory response due to the active disease, cardiac or pulmonary failure or advanced age, the prognosis may improve or worsen following inhalation anesthesia depending on the type of systemic pathology. The available data from reported clinical trials, as well as the

Indexed as

cellular responsesfree tissue transfersimmunomodulationmicrocirculationvolatile anesthetics

Identifiers

PMID36967859
PMCPMC10031674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.