Evidence map›Paper›PMID 36967818›Full record

ArticleFrontiers in aging neuroscience2023

Language impairment in Parkinson's disease: fMRI study of sentence reading comprehension.

Lubomira Novakova, Martin Gajdos, Jana Markova, Alice Martinkovicova, Zuzana Kosutzka, Jana Svantnerova, Peter Valkovic, Zsolt Csefalvay, Irena Rektorova

Open access · goldFull text read
In one paragraph

Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Language network disruption in patients with Lewy body diseases.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  2. Article
  3. Language dysfunction as a primary feature of cognitive decline in neurological populations.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Cognition and Activity of Daily Living Function in people with Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Lubomira NovakovaBrain and Mind Research, Central European Institute of Technology, Masaryk University, Brno, Czechia.
Martin GajdosBrain and Mind Research, Central European Institute of Technology, Masaryk University, Brno, Czechia.
Jana MarkovaDepartment of Communication Disorders, Faculty of Education, Comenius University, Bratislava, Slovakia.
Alice MartinkovicovaSecond Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Zuzana KosutzkaSecond Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Jana SvantnerovaSecond Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Peter ValkovicSecond Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Zsolt CsefalvayDepartment of Communication Disorders, Faculty of Education, Comenius University, Bratislava, Slovakia.
Irena RektorovaBrain and Mind Research, Central European Institute of Technology, Masaryk University, Brno, Czechia.
Comenius University Bratislava · SKCentral European Institute of Technology – Masaryk University · CZCentral European Institute of Technology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) affects the language processes, with a significant impact on the patients' daily communication. We aimed to describe specific alterations in the comprehension of syntactically complex sentences in patients with PD (PwPD) as compared to healthy controls (HC) and to identify the neural underpinnings of these deficits using a functional connectivity analysis of the striatum. A total of 20 patients PwPD and 15 HC participated in the fMRI study. We analyzed their performance of a Test of sentence comprehension (ToSC) adjusted for fMRI. A task-dependent functional connectivity analysis of the striatum was conducted using the psychophysiological interaction method (PPI). On the behavioral level, the PwPD scored significantly lower (mean ± sd: 77.3 ± 12.6) in the total ToSC score than the HC did (mean ± sd: 86.6 ± 8.0),

Indexed as

functional connectivitylanguage impairmentParkinson’s diseasesentence reading comprehensionstriatumtask fMRI

Identifiers

PMID36967818
PMCPMC10033839
OpenAlexW4323666785

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read7
measurements read5
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.