Evidence map›Paper›PMID 36967744›Full record

ArticlePediatric investigation2023

Response to magnesium sulfate and adrenocorticotropic hormone combination therapy for infantile spasms with failed first-line treatments.

Qiuhong Wang, Wen He, Yangyang Wang, Liying Liu, Mengna Zhang, Xiaoyan Yang, Liping Zou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qiuhong WangDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.ORCID https://orcid.org/0000-0002-8984-4925
Wen HeDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Yangyang WangDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Liying LiuDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Mengna ZhangDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Xiaoyan YangDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Liping ZouDepartment of Pediatrics Chinese PLA General Hospital The First Medical Center of Chinese PLA General Hospital Beijing China.
Chinese PLA General Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Infantile spasm (IS) is a kind of refractory epilepsy. The first-line treatments for IS are adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin. Objective: This study aimed to evaluate the efficacy of magnesium sulfate and ACTH (MgSO Methods: In this retrospective study, the clinical data of patients with IS who failed first-line treatments were collected in the Chinese PLA General Hospital. Patients received MgSO Results: A total of 229 patients with IS who failed the first-line treatments were collected. At the end of the MgSO Interpretation: For patients with IS who failed first-line treatments, in terms of the seizure-free rate and resolution of hypsarrhythmia on EEG, MgSO

Indexed as

Adrenocorticotropic hormoneEfficacyInfantile spasmsMagnesium sulfateTreatment

Identifiers

PMID36967744
PMCPMC10030695
OpenAlexW4323662108

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.