ArticleAnnals of biomedical engineering2023
The Influence of Minor Aortic Branches in Patient-Specific Flow Simulations of Type-B Aortic Dissection.
Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Computational analysis of haemodynamics and oxygen distribution in the patient-specific aorta during VA-ECMO under various clinical scenarios.Medical & biological engineering & computing · 2026Article
- Spectral Computed Tomography for the Detection and Characterization of Communications Between the True and the False Lumen in Aortic Dissections.Investigative radiology · 2026Article
- Impact of stent graft geometry on hemodynamics in superior mesenteric artery reconstruction after fenestrated/branched endovascular aneurysm repair.Frontiers in bioengineering and biotechnology · 2026Article
- Impact of Residual Intimal Flap Displacement Post-TEVAR on TBAD Haemodynamics in Compliant, Patient-specific CFD Simulations Informed by MRI.Annals of biomedical engineering · 2025Article
- Modeling Techniques and Boundary Conditions in Abdominal Aortic Aneurysm Analysis: Latest Developments in Simulation and Integration of Machine Learning and Data-Driven Approaches.Bioengineering (Basel, Switzerland) · 2025Review
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- Pediatric Cardiovascular Multiscale Modeling using a Functional Mock-up Interface.Cardiovascular engineering and technology · 2025Article
- Assessment of Aortic Dissection Remodeling With Patient-Specific Fluid-Structure Interaction Models.IEEE transactions on bio-medical engineering · 2025Article
- Computational Fluid Dynamics-Driven Comparison of Endovascular Treatment Strategies for Penetrating Aortic Ulcer.Journal of clinical medicine · 2025Article
- ML-ROM wall shear stress prediction in patient-specific vascular pathologies under a limited clinical training data regime.PloS one · 2025Article
- Estimating flow division in aortic branches of diseased aorta: a method for boundary condition specification in CFD analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Computational fluid dynamics modelling of hemodynamics in aortic aneurysm and dissection: a review.Frontiers in bioengineering and biotechnology · 2025Review
- A Monte Carlo Sensitivity Analysis for a Dimensionally Reduced-Order Model of the Aortic Dissection.Cardiovascular engineering and technology · 2024Article
- Morphologic prognostic factor for thoracoabdominal aortic dilation after acute type A dissection repair.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Stress Load and Ascending Aortic Aneurysms: An Observational, Longitudinal, Single-Center Study Using Computational Fluid Dynamics.Bioengineering (Basel, Switzerland) · 2024Article
- Aneurysmal growth in type-B aortic dissection: assessing the impact of patient-specific inlet conditions on key haemodynamic indices.Journal of the Royal Society, Interface · 2023Article
- Towards Reduced Order Models via Robust Proper Orthogonal Decomposition to capture personalised aortic haemodynamics.Journal of biomechanics · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Type-B aortic dissection (TBAD) is a disease in which a tear develops in the intimal layer of the descending aorta forming a true lumen and false lumen (FL). Because disease outcomes are thought to be influenced by haemodynamic quantities such as pressure and wall shear stress (WSS), their analysis via numerical simulations may provide valuable clinical insights. Major aortic branches are routinely included in simulations but minor branches are virtually always neglected, despite being implicated in TBAD progression and the development of complications. As minor branches are estimated to carry about 7-21% of cardiac output, neglecting them may affect simulation accuracy. We present the first simulation of TBAD with all pairs of intercostal, subcostal and lumbar arteries, using 4D-flow MRI (4DMR) to inform patient-specific boundary conditions. Compared to an equivalent case without minor branches, their inclusion improved agreement with 4DMR velocities, reduced time-averaged WSS (TAWSS) and transmural pressure and elevated oscillatory shear in regions where FL dilatation and calcification were observed in vivo. Minor branch inclusion resulted in differences of 60-75% in these metrics of potential clinical relevance, indicating a need to account for minor branch flow loss if simulation accuracy is sought.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.