Evidence map›Paper›PMID 36967398›Full record

ArticleEnvironmental health : a global access science source2023

Adult asthma associated with roadway density and housing in rural Appalachia: the Mountain Air Project (MAP).

W Jay Christian, John Flunker, Beverly May, Susan Westneat, Wayne T Sanderson, Nancy Schoenberg, Steven R Browning

Open access · goldFull text read
In one paragraph

Article in Environmental health : a global access science source, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Identifying risk factors for adverse lung health outcomes among rural Appalachian women.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

W Jay ChristianDepartment of Epidemiology and Environmental Health, College of Public Health, The University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA.
John FlunkerDepartment of Epidemiology and Environmental Health, College of Public Health, The University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA.
Beverly MayDepartment of Epidemiology and Environmental Health, College of Public Health, The University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA.
Susan WestneatDepartment of Epidemiology and Environmental Health, College of Public Health, The University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA.
Wayne T SandersonDepartment of Biosystems and Agricultural Engineering, College of Agriculture, Food, and Environment, University of Kentucky, Lexington, KY, USA.
Nancy SchoenbergBehavioral Science, College of Medicine, University of Kentucky, Lexington, KY, USA.
Steven R BrowningDepartment of Epidemiology and Environmental Health, College of Public Health, The University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA. srbrown@uky.edu.
University of Kentucky · US

Funding

Community-Engaged Research and Action to Reduce Respiratory Disease in AppalachiaR01ES024771 · NIEHS · UNIVERSITY OF KENTUCKY · PI BROWNING, STEVEN R, SCHOENBERG, NANCY E. · 2015 to 2019
$2.5M
NIEHS NIH HHS R01 ES024771NIOSH CDC HHS U54 OH007547
6 · The paper itself

Abstract

backgroundAppalachian Kentucky is a rural area with a high prevalence of asthma among adults. The relative contribution of environmental exposures in the etiology of adult asthma in these populations has been understudied.

objectiveThis manuscript describes the aims, study design, methods, and characteristics of participants for the Mountain Air Project (MAP), and focuses on associations between small area environmental exposures, including roadways and mining operations, and lifetime and current asthma in adults.

methodsA cohort of residents, aged 21 and older, in two Kentucky counties, was enrolled in a community-based, cross-sectional study. Stratified cluster sampling was used to select small geographic areas denoted as 14-digit USGS hydrologic units (HUCs). Households were enumerated within selected HUCs. Community health workers collected in-person interviews. The proximity of nearby active and inactive coal mining operations, density of oil and gas operations, and density of roadways were characterized for all HUCs. Poisson regression analyses were used to estimate adjusted prevalence ratios.

resultsFrom 1,459 eligible households contacted, 1,190 individuals were recruited, and 972 persons completed the interviews. The prevalence of lifetime asthma was 22.8%; current asthma was 16.3%. Adjusting for covariates, roadway density was positively associated with current asthma in the second (aPR = 1.61; 95% CI 1.04-2.48) and third tertiles (aPR = 2.00; 95% CI 1.32-3.03). Increased risk of current asthma was associated with residence in public, multi-unit housing (aPR = 2.01; 95% CI 1.27-3.18) compared to a residence in a single-family home. There were no notable associations between proximity to coal mining and oil and gas operations and asthma prevalence.

conclusionsThis study suggests that residents in rural areas with higher roadway density and those residing in public housing units may be at increased risk for current asthma after accounting for other known risk factors. Confirming the role of traffic-related particulates in producing high asthma risk among adults in this study contributes to the understanding of the multiple environmental exposures that influence respiratory health in the Appalachia region.

Indexed as

AsthmaAdultAppalachian RegionCross-Sectional StudiesEnvironmental ExposureHumansPublic HousingAdultAppalachiaAsthmaEpidemiologyMining

Identifiers

PMID36967398
PMCPMC10041800
OpenAlexW4361011624

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read4
measurements read63
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.