Evidence map›Paper›PMID 36967031›Full record

ReviewPhysiology & behavior2023

The organizational role of ovarian hormones during puberty on risk for binge-like eating in rats.

Britny A Hildebrandt, Jenna R Lee, Kristen M Culbert, Cheryl L Sisk, Alexander W Johnson, Kelly L Klump

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Physiology & behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Britny A HildebrandtDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jenna R LeeDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
Kristen M CulbertDepartment of Psychology, Michigan State University, East Lansing, MI, USA.
Cheryl L SiskDepartment of Psychology, Michigan State University, East Lansing, MI, USA; Neuroscience Program, Michigan State University, East Lansing, MI, USA.
Alexander W JohnsonDepartment of Psychology, Michigan State University, East Lansing, MI, USA; Neuroscience Program, Michigan State University, East Lansing, MI, USA.
Kelly L KlumpDepartment of Psychology, Michigan State University, East Lansing, MI, USA. Electronic address: klump@msu.edu.
Michigan State University · USUniversity of Pittsburgh · US

Funding

A Twin Study of exogenous hormone exposure and risk for binge eatingR01MH111715 · NIMH · MICHIGAN STATE UNIVERSITY · PI KLUMP, KELLY L · 2017 to 2021
$4.0M
NIMH NIH HHS R01 MH111715
6 · The paper itself

Abstract

Puberty is a high-risk period for the development of dysregulated eating, including binge eating. While risk for binge eating in animals and humans increases in both males and females during puberty, the increased prevalence is significantly greater in females. Emerging data suggest that the organizational effects of gonadal hormones may contribute to the female preponderance of binge eating. In this narrative review, we discuss studies conducted in animals that have examined these organizational effects as well as the neural systems that may serve as intermediary mechanisms. Relatively few studies have been conducted, but data thus far suggest that pubertal estrogens may organize risk for binge eating, potentially by altering key circuits in brain reward pathways. These promising results highlight the need for future studies to directly test organizational effects of pubertal hormones using hormone replacement techniques and circuit-level manipulations that can identify pathways contributing to binge eating across development.

Indexed as

Binge-Eating DisorderBulimiaAnimalsEstrogensFemaleGonadal HormonesHumansMalePubertyRatsSexual MaturationEstrogensGonadal HormonesAdolescentEating disordersEstrogensGonadal hormonesPalatable foodRodents

Identifiers

PMID36967031
PMCPMC10121844
OpenAlexW4360983671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.