Evidence map›Paper›PMID 36967028›Full record

Trial reportValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2023

Cost-Effectiveness and Long-Term Savings of the Bright Bodies Intervention for Childhood Obesity.

Sydney Pryor, Mary Savoye, Paulina Nowicka, Gary Price, Mona Sharifi, Reza Yaesoubi

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Water First School Water Promotion and Access Intervention: A Cost Analysis Study.Journal of the Academy of Nutrition and Dietetics · 2025
    Trial
  4. Review
  5. Management of Childhood Obesity.International journal of molecular sciences · 2026
    Review
  6. Article
  7. Article
  8. Mapping IWQOL-Lite onto EQ-5D-5L and SF-6Dv2 among overweight and obese population in China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sydney PryorDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA; Department of Health Policy and Management, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Mary SavoyeDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Paulina NowickaDepartment of Food Studies, Nutrition and Dietetics, Uppsala University, Uppsala, Sweden.
Gary PriceDepartment of Surgery, Yale School of Medicine, New Haven, CT, USA.
Mona SharifiDepartment of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
Reza YaesoubiDepartment of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA. Electronic address: reza.yaesoubi@yale.edu.
Yale University · USMilken Institute · USUppsala University · SE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Dissemination and Implementation of the Bright Bodies Intervention for Childhood ObesityR01HL151603 · NHLBI · YALE UNIVERSITY · PI Mahnoosh Sharifi · 2020 to 2026
$4.7M
Using Electronic Health Records to Support Decision-Making in Pediatric Obesity CareK08HS024332 · AHRQ · YALE UNIVERSITY · PI SHARIFI, MAHNOOSH · 2016 to 2018
$461k
AHRQ HHS K08 HS024332NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL151603
6 · The paper itself

Abstract

objectivesTo estimate the cost and cost-effectiveness of Bright Bodies, a high-intensity, family-based intervention that has been demonstrated to improve body mass index (BMI) among children with obesity in a randomized controlled trial.

methodsWe developed a microsimulation model to project 10-year BMI trajectories of 8 to 16-year-old children with obesity, using data from the National Longitudinal Surveys and Centers for Disease Control and Prevention growth charts, and we validated the model using data from the Bright Bodies trial and a follow-up study. We used the trial data to estimate the average reduction in BMI per person-year over 10 years and the incremental costs of Bright Bodies, compared with the traditional clinical weight management (control), from a health system's perspective in 2020 US dollars. Using results from studies of Medical Expenditure Panel Survey data, we projected the long-term obesity-related medical expenditure.

resultsIn the primary analysis, assuming depreciating effects postintervention, Bright Bodies is expected to reduce a participant's BMI by 1.67 kg/m

conclusionsAlthough resource-intensive, our findings suggest that Bright Bodies is cost-saving compared to the clinical control by averting future obesity-related healthcare costs among children with obesity.

Indexed as

Pediatric ObesityAdolescentBody Mass IndexChildCost-Benefit AnalysisFollow-Up StudiesHumanscomputer simulationeconomic evaluationmodelingobesity managementpediatric obesity

Identifiers

PMID36967028
PMCPMC10518029
OpenAlexW4360962798

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.