Evidence map›Paper›PMID 36966972›Full record

ReviewPharmacology & therapeutics2023

Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases.

Chu Chen

Open access · hybridAbstract readReview
In one paragraph

Review in Pharmacology & therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Neurotransmitter Systems in Alzheimer's Disease.Current issues in molecular biology · 2026
    Review
  8. Review
  9. Article
  10. Ageing, Neurodegeneration and the Endocannabinoid System.Current topics in behavioral neurosciences · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. International journal of molecular sciences · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chu ChenDepartment of Cellular and Integrative Physiology, Center for Biomedical Neuroscience, Joe R. and Teresa Lozano Long School of Medicine, University of Texas Health San Antonio, San Antonio, TX 78229, USA. Electronic address: chenc7@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · US

Funding

Endocannabinoids in neurodegenerative diseasesRF1NS076815 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHEN, CHU · 2023 to 2023
$2.2M
Traumatic brain injury and Alzheimer's diseaseR01AG058621 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHEN, CHU · 2018 to 2022
$1.9M
Endocannabinoid Metabolism and Synaptic FunctionR01MH113535 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHEN, CHU · 2018 to 2022
$1.9M
NIA NIH HHS R01 AG058621NIMH NIH HHS R01 MH113535NINDS NIH HHS RF1 NS076815
6 · The paper itself

Abstract

Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid and is a full agonist of G-protein-coupled cannabinoid receptors (CB1R and CB2R), which are targets of Δ

Indexed as

Neurodegenerative DiseasesNeuroprotective AgentsAnimalsArachidonic AcidsEndocannabinoidsGlyceridesNeuroinflammatory DiseasesArachidonic AcidsEndocannabinoidsGlyceridesglyceryl 2-arachidonateNeuroprotective Agents2-ArachidonoylglycerolAlzheimer’s diseaseEndocannabinoidMonoacylglycerol lipaseNeurodegenerative diseaseTraumatic brain injury

Identifiers

PMID36966972
PMCPMC10123871
OpenAlexW4360841679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.