Evidence map›Paper›PMID 36966280›Full record

ArticleBMC microbiology2023

Exploration of lung mycobiome in the patients with non-small-cell lung cancer.

Yiming Zhao, Junqi Yi, Juanjuan Xiang, Wei Jia, Anqi Chen, Liyu Chen, Leliang Zheng, Wen Zhou, Minghua Wu, Zheng Yu and 1 more

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
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  9. Review
  10. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  11. Review
  12. Impact of Saharan Dust andInternational journal of molecular sciences · 2025
    Article
  13. Article
  14. Unraveling the Fungi-Cancer Connection.Research (Washington, D.C.) · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. The Coexistence ofInternational journal of molecular sciences · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yiming Zhao *Department of Thoracic Surgery, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Junqi Yi *Department of Thoracic Surgery, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Juanjuan XiangHunan Key Laboratory of Early Diagnosis and Precise Treatment of Lung Cancer, Changsha, Hunan, China.
Wei JiaSchool of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, China.
Anqi ChenDepartment of Thoracic Surgery, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Liyu ChenDepartment of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Leliang ZhengNHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Wen ZhouNHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Minghua WuNHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Zheng YuDepartment of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China. yuzheng@csu.edu.cn.
Jingqun TangDepartment of Thoracic Surgery, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China. tangjq@csu.edu.cn.
Central South University · CNChangsha Medical University · CNHong Kong Baptist University · HKSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the Human Microbiome Project (HMP) progresses, the relationship between microbes and human health has been receiving increasing attention. A growing number of reports support the correlation between cancer and microbes. However, most studies have focused on bacteria, rather than fungal communities. In this study, we studied the alteration in lung mycobiome in patients with non-small-cell lung cancer (NSCLC) using metagenomic sequencing and qPCR. The higher fungal diversity and more complex network were observed in the patients with NSCLC. In addition, Alternaria arborescens was found as the most relevant fungus to NSCLC, and the enrichment of it in cancerous tissue was also detected. This study proposes that the changes in fungal communities may be closely related to lung cancer, and provides insights into further exploration the relationship between lung cancer and fungi.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsMycobiomeFungiHumansLungAlternaria arborescensMycobiomeNon-small-cell lung cancer

Identifiers

PMID36966280
PMCPMC10039514
OpenAlexW4360949217

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read41
table measurements read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.