Evidence map›Paper›PMID 36965810›Full record

ArticleEnvironmental research2023

Industry, occupation, and exposure history of mesothelioma patients in the U.S. National Mesothelioma Virtual Bank, 2006-2022.

Yuhe Gao, Jacek M Mazurek, Yaming Li, David Blackley, David N Weissman, Shirley V Burton, Waqas Amin, Douglas Landsittel, Michael J Becich, Ye Ye

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yuhe GaoDepartment of Biomedical Informatics, School of Medicine, University of Pittsburgh, USA.
Jacek M MazurekRespiratory Health Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, USA.
Yaming LiDepartment of Biomedical Informatics, School of Medicine, University of Pittsburgh, USA.
David BlackleyRespiratory Health Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, USA.
David N WeissmanRespiratory Health Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, USA.
Shirley V BurtonRespiratory Health Division, National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, USA.
Waqas AminClinical and Translational Sciences Institute, School of Medicine, Indiana University, USA.
Douglas LandsittelEpidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, USA.
Michael J BecichDepartment of Biomedical Informatics, School of Medicine, University of Pittsburgh, USA.
Ye YeDepartment of Biomedical Informatics, School of Medicine, University of Pittsburgh, USA. Electronic address: yey5@pitt.edu.
National Institute for Occupational Safety and Health · USUniversity of Pittsburgh · USIndiana University · USIndiana University Bloomington · US

Funding

Sustaining the Expansion of the National Mesothelioma Virtual Bank (NMVB)U24OH009077 · OH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECICH, MICHAEL JOHN, DACIC, SANJA · 2008 to 2025
$18.0M
Intramural CDC HHS CC999999NIOSH CDC HHS U24 OH009077
6 · The paper itself

Abstract

backgroundMalignant mesothelioma is associated with environmental and occupational exposure to certain mineral fibers, especially asbestos. This study aims to examine work histories of mesothelioma patients and their survival time.

methodUsing the NIOSH Industry and Occupation Computerized Coding System, we mapped occupations and industries recorded for 748 of 1444 patients in the U.S. National Mesothelioma Virtual Bank (NMVB) during the period 2006-2022. Descriptive and survival analyses were conducted.

resultsAmong the 1023 industries recorded for those having mesothelioma, the most frequent cases were found for those in manufacturing (n = 225, 22.0%), construction (138, 13.5%), and education services (66, 6.5%); among the 924 occupation records, the most frequent cases were found for those in construction and extraction (174, 18.8%), production (145, 15.7%), and management (84, 9.1%). Males (583) or persons aged >40 years (658) at the time of diagnosis tended to have worked in industries traditionally associated with mesothelioma (e.g., construction), while females (163) or persons aged 20-40 years (27) tended to have worked in industries not traditionally associated with mesothelioma (e.g., health care). Asbestos, unknown substances, and chemical solvents were the most frequently reported exposure, with females most often reporting an unknown substance. A multi-variable Cox Hazard Regression analysis showed that significant prognostic factors associated with decreased survival in mesothelioma cases are sex (male) and work experience in utility-related industry, while factor associated with increased survival are epithelial or epithelioid histological type, prior history of surgery and immunotherapy, and industry experience in accommodation and food services.

conclusionThe NMVB has the potential of serving as a sentinel surveillance mechanism for identifying industries and occupations not traditionally associated with mesothelioma. Results indicate the importance of considering all potential sources of asbestos exposures including occupational, environmental, and extra-occupational exposures when evaluating mesothelioma patients and advising family members.

Indexed as

AsbestosMesotheliomaMesothelioma, MalignantOccupational DiseasesOccupational ExposureFemaleHumansIndustryMaleOccupationsAsbestosAsbestosMesotheliomaOccupational exposureSexSurvivalWork history

Identifiers

PMID36965810
PMCPMC10994633
OpenAlexW4360611279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.