Evidence map›Paper›PMID 36964979›Full record

ArticleInternational journal of experimental pathology2023

Arginine vasopressin deficiency and conivaptan (a V1a-V2 receptor antagonist) treatment reverses liver damage and fibrosis in rats with chronic portocaval anastomosis.

Yesenia Danyeli Navarro-Gonzalez, Javier Ventura-Juarez, Martín Humberto Muñoz-Ortega, Daniel González-Blas, Argelia Calvillo-Robedo, Manuel-Enrique Avila-Blanco, Fernando Valdez-Urias, Andrés Quintanar-Stephano

Open access · greenAbstract read
In one paragraph

Article in International journal of experimental pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yesenia Danyeli Navarro-GonzalezDepartamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Javier Ventura-JuarezDepartamento de Morfología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Martín Humberto Muñoz-OrtegaDepartamento de Química, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.ORCID 0000-0002-1961-6919
Daniel González-BlasDepartamento de Patología, Hospital General ISSSTE, Aguascalientes, Mexico.
Argelia Calvillo-RobedoDepartamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Manuel-Enrique Avila-BlancoDepartamento de Morfología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Fernando Valdez-UriasDepartamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Andrés Quintanar-StephanoDepartamento de Fisiología y Farmacología, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Aguascalientes, Mexico.
Autonomous University of Aguascalientes · MXInstitute for Social Security and Services for State Workers · MX

Funding

Consejo Nacional de Ciencia y Tecnología 221262 (AQS)Consejo Nacional de Ciencia y Tecnología 241312Consejo Nacional de Ciencia y Tecnología A1-S-21375 (MMO)Universidad Autónoma de Aguascalientes, Mexico PIBB19-11N (MMO)Universidad Autónoma de Aguascalientes, Mexico PIFF19-2 (AQS)
6 · The paper itself

Abstract

Arginine vasopressin (AVP) is a naturally occurring hormone synthesized in the hypothalamus. AVP demonstrates pro-fibrotic effects as it stimulates hepatic stellate cells to secrete transforming growth factor-β (TGF-β) and collagen. Previous work in liver cirrhotic (CCL

Indexed as

Diabetes Insipidus, NeurogenicReceptors, VasopressinAnastomosis, SurgicalAnimalsAntidiuretic Hormone Receptor AntagonistsArginineArginine VasopressinBenzazepinesCricetinaeLiver CirrhosisRatsAntidiuretic Hormone Receptor AntagonistsArginineArginine VasopressinBenzazepinesconivaptanReceptors, Vasopressinarginine vasopressinconivaptancytokinesliver fibrosisportocaval anastomosis

Identifiers

PMID36964979
PMCPMC10349233
OpenAlexW4360946328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.